Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 66046..67682 Replicon chromosome
Accession NZ_CP025781
Organism Iodobacter fluviatilis strain PCH194

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag C1H71_RS00355 Protein ID WP_130108082.1
Coordinates 66046..67347 (-) Length 434 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag C1H71_RS00360 Protein ID WP_130104791.1
Coordinates 67386..67682 (-) Length 99 a.a.

Genomic Context

C1H71_RS00325C1H71_RS00330C1H71_RS00340C1H71_RS00345C1H71_RS00350C1H71_RS00335C1H71_RS00355C1H71_RS00360C1H71_RS00365C1H71_RS00370C1H71_RS00375C1H71_RS00380C1H71_RS00385
Location: 61295..62305 (1011 bp)
Type: Others
Protein ID: WP_130104786.1
Location: 62566..62760 (195 bp)
Type: Others
Protein ID: WP_130104787.1
Location: 63453..64370 (918 bp)
Type: Others
Protein ID: WP_130104789.1
Location: 64525..65022 (498 bp)
Type: Others
Protein ID: WP_130108081.1
Location: 65077..65889 (813 bp)
Type: Others
Protein ID: WP_130104790.1
Location: 62817..63314 (498 bp)
Type: Others
Protein ID: WP_188053452.1
Location: 66046..67347 (1302 bp)
Type: Toxin
Protein ID: WP_130108082.1
Location: 67386..67682 (297 bp)
Type: Antitoxin
Protein ID: WP_130104791.1
Location: 67909..69000 (1092 bp)
Type: Others
Protein ID: WP_130108083.1
Location: 69144..70319 (1176 bp)
Type: Others
Protein ID: WP_130104792.1
Location: 70485..71405 (921 bp)
Type: Others
Protein ID: WP_130104793.1
Location: 71402..71986 (585 bp)
Type: Others
Protein ID: WP_188053454.1
Location: 72278..72649 (372 bp)
Type: Others
Protein ID: WP_188053456.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C1H71_RS0032561295..62305+1011WP_130104786.1nucleoid-associated protein-
C1H71_RS0033062566..62760+195WP_130104787.1hypothetical protein-
C1H71_RS0033562817..63314-498WP_188053452.1GNAT family N-acetyltransferase-
C1H71_RS0034063453..64370+918WP_130104789.1LysR family transcriptional regulator ArgP-
C1H71_RS0034564525..65022+498WP_130108081.1DUF4442 domain-containing protein-
C1H71_RS0035065077..65889+813WP_130104790.1crotonase/enoyl-CoA hydratase family protein-
C1H71_RS0035566046..67347-1302WP_130108082.1type II toxin-antitoxin system HipA family toxinToxin
C1H71_RS0036067386..67682-297WP_130104791.1helix-turn-helix domain-containing proteinAntitoxin
C1H71_RS0036567909..69000-1092WP_130108083.1D-alanine--D-alanine ligase-
C1H71_RS0037069144..70319-1176WP_130104792.1O-succinylhomoserine sulfhydrylase-
C1H71_RS0037570485..71405-921WP_130104793.1type II secretion system minor pseudopilin GspK-
C1H71_RS0038071402..71986-585WP_188053454.1type II secretion system minor pseudopilin GspJ-
C1H71_RS0038572278..72649-372WP_188053456.1type II secretion system minor pseudopilin GspI-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(1-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-66)


Sequences

Toxin        


Download         Length: 434 a.a.        Molecular weight: 47586.67 Da        Isoelectric Point: 8.3302

>T91955 WP_130108082.1 NZ_CP025781:c67347-66046 [Iodobacter fluviatilis]
MNGVLVGEWSRAPDGERLAYSPYWVKYRKGRPLSLSLPFTPGNQVYKGELVSAFFDNLLPDSDAIRRRLALRYQSASLAP
FDLLAVLGRDCVGAIQLLVPDESPDHLFTIKGEVLTEADIARLLRNSTVNGALGPTDLEGDLRLSIAGAQEKTALLYHKG
QWLLPEGSTPTTHIFKLPMGLVGNMQADMQTSVENEWLCAKIVAAYGLDVAACDIGRFEDQKALIVRRFDRKLSSDGRWI
IRLPQEDMCQASGTHPLRKYQIDGGPSMGQIMDILRGSSRAEQDRRDFFKAQLVFWLLAATDGHAKNFSVFQIPGGRFQS
TPLYDILSAHPIIGTGRNQLAPQKVKLAMAVRGSSNHYLLDKIQRRHWLAQARQAGLGSNVAEAIIAELLAATAEVLKSV
SAQLPTDFPPSLADAILDGVQRQCNKLAAMTAI

Download         Length: 1302 bp

>T91955 NZ_CP025781:c67347-66046 [Iodobacter fluviatilis]
ATGAATGGCGTGCTGGTGGGCGAGTGGTCCAGAGCGCCAGATGGCGAGCGCCTTGCGTATTCGCCTTATTGGGTAAAGTA
CCGCAAAGGTCGGCCTTTATCTTTGTCTTTGCCGTTTACGCCGGGTAATCAGGTTTATAAAGGCGAGCTGGTCAGCGCTT
TTTTTGACAATCTTTTACCCGATAGTGATGCCATACGCAGGCGCTTGGCATTGCGTTATCAATCAGCCAGCCTAGCACCA
TTTGATTTGCTGGCCGTGCTGGGGCGGGATTGCGTAGGGGCTATTCAGCTGCTTGTGCCTGATGAGTCCCCCGATCATTT
GTTTACGATTAAGGGCGAGGTACTTACTGAGGCCGACATTGCCCGCTTGCTTCGTAATTCAACGGTCAACGGGGCGCTGG
GGCCGACTGATTTAGAGGGTGATTTGCGGCTATCTATTGCCGGTGCTCAGGAGAAAACAGCACTGCTTTATCATAAAGGG
CAGTGGTTATTGCCCGAAGGCAGCACACCTACCACGCATATTTTTAAGCTGCCTATGGGCTTGGTCGGCAATATGCAGGC
CGATATGCAAACATCGGTGGAAAACGAATGGCTATGCGCCAAGATTGTTGCCGCTTATGGCTTGGATGTAGCGGCCTGTG
ATATTGGGCGTTTTGAGGATCAGAAAGCATTGATTGTTCGGCGCTTTGATCGAAAATTATCGAGTGATGGCCGTTGGATT
ATCCGCTTGCCGCAGGAGGATATGTGTCAGGCCAGCGGCACTCATCCTTTAAGGAAGTATCAGATTGATGGTGGCCCCAG
CATGGGGCAGATTATGGATATCTTGCGTGGATCAAGCCGCGCGGAACAAGATCGGCGTGATTTTTTTAAAGCGCAATTGG
TATTCTGGCTGCTGGCCGCAACCGATGGCCATGCCAAGAATTTTAGCGTGTTCCAAATACCCGGCGGGCGATTCCAATCC
ACGCCCCTTTACGACATCCTTTCTGCGCACCCGATTATCGGCACAGGCCGCAATCAGCTAGCACCACAAAAAGTAAAGTT
AGCCATGGCGGTGCGGGGCAGTAGCAATCATTACTTGCTGGATAAAATACAGCGTAGACACTGGTTGGCTCAGGCACGCC
AAGCAGGGCTGGGGAGTAATGTGGCAGAAGCAATCATTGCTGAGCTGCTTGCTGCTACCGCTGAAGTATTAAAGAGTGTG
AGCGCTCAATTGCCCACCGATTTTCCACCGAGCTTGGCAGATGCCATCTTGGATGGTGTGCAGCGGCAATGTAATAAGCT
CGCAGCAATGACGGCTATCTAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10830.27 Da        Isoelectric Point: 4.7023

>AT91955 WP_130104791.1 NZ_CP025781:c67682-67386 [Iodobacter fluviatilis]
VNYPLQTLSQLRPVLQGFRKANNLTQAALAERLGITQQTYAQLEANPASASVERLFKVLRALDVELWLSHASVTEPDVAD
AVVMAKETQLADPAQENW

Download         Length: 297 bp

>AT91955 NZ_CP025781:c67682-67386 [Iodobacter fluviatilis]
GTGAACTATCCTCTTCAAACCCTTTCTCAGTTGCGGCCTGTTTTACAGGGGTTTCGCAAGGCGAATAATCTGACGCAAGC
GGCTTTGGCGGAGCGCTTGGGGATTACTCAGCAAACTTATGCCCAGCTAGAGGCAAACCCGGCATCGGCCAGCGTAGAGC
GCTTATTTAAAGTGTTGCGTGCTTTGGATGTGGAGTTGTGGCTAAGCCACGCTTCTGTTACAGAGCCAGATGTGGCAGAT
GCCGTGGTGATGGCGAAAGAGACGCAATTGGCTGATCCCGCTCAGGAAAACTGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References