Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 4639125..4639488 | Replicon | chromosome |
Accession | NZ_CP025750 | ||
Organism | Xanthomonas campestris pv. campestris strain 3811 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | G0CKD4 |
Locus tag | C1H20_RS20935 | Protein ID | WP_011270059.1 |
Coordinates | 4639125..4639259 (-) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | Q8P3Z2 |
Locus tag | C1H20_RS20940 | Protein ID | WP_011038999.1 |
Coordinates | 4639336..4639488 (-) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C1H20_RS20915 | 4634389..4636041 | - | 1653 | WP_043890286.1 | M28 family peptidase | - |
C1H20_RS20920 | 4636206..4637150 | - | 945 | WP_043890287.1 | MBL fold metallo-hydrolase | - |
C1H20_RS20925 | 4637234..4638523 | - | 1290 | WP_029217012.1 | tryptophan--tRNA ligase | - |
C1H20_RS20930 | 4638683..4638892 | - | 210 | WP_011038998.1 | CsbD family protein | - |
C1H20_RS20935 | 4639125..4639259 | - | 135 | WP_011270059.1 | entericidin A/B family lipoprotein | Toxin |
C1H20_RS20940 | 4639336..4639488 | - | 153 | WP_011038999.1 | entericidin A/B family lipoprotein | Antitoxin |
C1H20_RS20945 | 4639599..4640522 | - | 924 | WP_012439504.1 | arginase | - |
C1H20_RS20950 | 4640836..4641297 | + | 462 | WP_012439505.1 | roadblock/LC7 domain-containing protein | - |
C1H20_RS20955 | 4641380..4641739 | + | 360 | WP_011039002.1 | hypothetical protein | - |
C1H20_RS20960 | 4641842..4642759 | + | 918 | WP_012439506.1 | hypothetical protein | - |
C1H20_RS20965 | 4642756..4643298 | + | 543 | WP_012439507.1 | GTPase | - |
C1H20_RS20970 | 4643633..4644316 | + | 684 | WP_011039005.1 | dTMP kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4431.27 Da Isoelectric Point: 9.3487
>T91900 WP_011270059.1 NZ_CP025750:c4639259-4639125 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
Download Length: 135 bp
>T91900 NZ_CP025750:c4639259-4639125 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5173.15 Da Isoelectric Point: 8.2782
>AT91900 WP_011038999.1 NZ_CP025750:c4639488-4639336 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC
Download Length: 153 bp
>AT91900 NZ_CP025750:c4639488-4639336 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H2XDQ0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | Q8P3Z2 |