91900

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4639125..4639488 Replicon chromosome
Accession NZ_CP025750
Organism Xanthomonas campestris pv. campestris strain 3811

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag C1H20_RS20935 Protein ID WP_011270059.1
Coordinates 4639125..4639259 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag C1H20_RS20940 Protein ID WP_011038999.1
Coordinates 4639336..4639488 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1H20_RS20915 4634389..4636041 - 1653 WP_043890286.1 M28 family peptidase -
C1H20_RS20920 4636206..4637150 - 945 WP_043890287.1 MBL fold metallo-hydrolase -
C1H20_RS20925 4637234..4638523 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
C1H20_RS20930 4638683..4638892 - 210 WP_011038998.1 CsbD family protein -
C1H20_RS20935 4639125..4639259 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
C1H20_RS20940 4639336..4639488 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
C1H20_RS20945 4639599..4640522 - 924 WP_012439504.1 arginase -
C1H20_RS20950 4640836..4641297 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
C1H20_RS20955 4641380..4641739 + 360 WP_011039002.1 hypothetical protein -
C1H20_RS20960 4641842..4642759 + 918 WP_012439506.1 hypothetical protein -
C1H20_RS20965 4642756..4643298 + 543 WP_012439507.1 GTPase -
C1H20_RS20970 4643633..4644316 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T91900 WP_011270059.1 NZ_CP025750:c4639259-4639125 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T91900 NZ_CP025750:c4639259-4639125 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT91900 WP_011038999.1 NZ_CP025750:c4639488-4639336 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT91900 NZ_CP025750:c4639488-4639336 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0


Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References