Detailed information of TA system TA091899

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 1234988..1235766
• Replicon: chromosome
• Accession: NZ_CP025750
• Organism: Xanthomonas campestris pv. campestris strain 3811

Toxin (Protein)

• Gene name: TacT2
• Uniprot ID: Q8P667
• Locus tag: C1H20_RS05410
• Protein ID: WP_011038220.1
• Coordinates: 1234988..1235479 (-)
• Length: 164 a.a.

Antitoxin (Protein)

• Gene name: TacA2
• Uniprot ID: Q8P668
• Locus tag: C1H20_RS05415
• Protein ID: WP_011038219.1
• Coordinates: 1235476..1235766 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1H20_RS05390	1231239..1232114	+	876	WP_016945000.1	30S ribosomal protein S6--L-glutamate ligase	-
C1H20_RS05395	1232337..1232810	+	474	WP_012437597.1	hypothetical protein	-
C1H20_RS05400	1232841..1233518	+	678	WP_003490678.1	response regulator transcription factor	-
C1H20_RS05405	1233511..1234845	+	1335	WP_012437598.1	HAMP domain-containing histidine kinase	-
C1H20_RS05410	1234988..1235479	-	492	WP_011038220.1	GNAT family N-acetyltransferase	Toxin
C1H20_RS05415	1235476..1235766	-	291	WP_011038219.1	DUF1778 domain-containing protein	Antitoxin
C1H20_RS05420	1235841..1236242	-	402	WP_012437599.1	type I toxin-antitoxin system SymE family toxin	-
C1H20_RS05430	1236774..1237397	-	624	WP_011038217.1	dephospho-CoA kinase	-
C1H20_RS05435	1237411..1238274	-	864	WP_012437600.1	A24 family peptidase	-
C1H20_RS05440	1238281..1239540	-	1260	WP_012437601.1	type II secretion system F family protein	-
C1H20_RS05445	1239892..1240311	+	420	WP_102650932.1	pilin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (42-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (1-95)

Sequences

Toxin

Protein

• Length: 164 a.a.
• Molecular weight: 17638.31 Da
• Isoelectric Point: 8.1192

>T91899 WP_011038220.1 NZ_CP025750:c1235479-1234988 [Xanthomonas campestris pv. campestris]
MTVSAPEPLTAHHRVEPFASGVESLDHWLKRRALKNQATGASRTFVACEDDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALMQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Nucleotide

• Length: 492 bp

>T91899 NZ_CP025750:c1235479-1234988 [Xanthomonas campestris pv. campestris]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTCGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGGACCTTCGTTGCCTGCGAGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTGGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGGAGGCTTGCTGTTGACCAATCCCTGCATGGCAGAGGTTTTGGCCGCGCCCTGATGCAGGA
TGCTGGCAAGCGCATCTTGCATGCGGCCGACACCATCGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGGCGGACGCCA
AGGCGTTTTACGAGCGCATCGGCTTCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10678.23 Da
• Isoelectric Point: 10.5480

>AT91899 WP_011038219.1 NZ_CP025750:c1235766-1235476 [Xanthomonas campestris pv. campestris]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLITASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Nucleotide

• Length: 291 bp

>AT91899 NZ_CP025750:c1235766-1235476 [Xanthomonas campestris pv. campestris]
ATGTCCACACCCAACACTACGCCTGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCACGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA

Structures

Toxin

• AlphaFold DB: Q8P667

Antitoxin

• AlphaFold DB: Q8P668