Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2812291..2812562 Replicon chromosome
Accession NZ_CP025747
Organism Escherichia coli strain ML35

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2812329..2812432 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2812291..2812562 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1I23_RS15140 2809448..2810887 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
C1I23_RS15145 2811005..2811241 + 237 WP_001295499.1 DUF1480 family protein -
C1I23_RS15150 2811346..2811537 + 192 WP_000457842.1 YebW family protein -
C1I23_RS15155 2811538..2812194 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2812291..2812562 + 272 - - Antitoxin
- 2812329..2812432 - 104 - - Toxin
C1I23_RS15160 2812590..2812931 - 342 WP_000976476.1 YebY family protein -
C1I23_RS15165 2812944..2813816 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
C1I23_RS15170 2813820..2814194 - 375 WP_102597174.1 CopC domain-containing protein YobA -
C1I23_RS15175 2814333..2814563 + 231 WP_000916763.1 DNA polymerase III subunit theta -
C1I23_RS15180 2814665..2815321 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
C1I23_RS15185 2815345..2816007 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T91881 NZ_CP025747:c2812432-2812329 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT91881 NZ_CP025747:2812291-2812562 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References