Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 32..591 Replicon plasmid pFORC79_2
Accession NZ_CP025737
Organism Salmonella enterica strain FORC_079

Toxin (Protein)


Gene name relE Uniprot ID V0SVC8
Locus tag FORC79_RS24370 Protein ID WP_000421272.1
Coordinates 316..591 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V0SRR3
Locus tag FORC79_RS24365 Protein ID WP_001387467.1
Coordinates 32..316 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC79_RS24365 32..316 + 285 WP_001387467.1 ribbon-helix-helix protein, CopG family Antitoxin
FORC79_RS24370 316..591 + 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC79_RS24375 697..990 + 294 WP_001105060.1 hypothetical protein -
FORC79_RS24380 1025..1153 - 129 Protein_3 transposase -
FORC79_RS24385 1186..2355 - 1170 WP_001072355.1 hypothetical protein -
FORC79_RS24395 2848..3155 + 308 Protein_5 type II toxin-antitoxin system ParD family antitoxin -
FORC79_RS24405 3498..3680 + 183 WP_042344623.1 hypothetical protein -
FORC79_RS24410 3801..4541 + 741 WP_001066953.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..99333 99333


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-109)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11810.03 Da        Isoelectric Point: 12.7590

>T91857 WP_000421272.1 NZ_CP025737:316-591 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKK

Download         Length: 276 bp

>T91857 NZ_CP025737:316-591 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 12194.55 Da        Isoelectric Point: 12.7731

>AT91857 WP_001387467.1 NZ_CP025737:32-316 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKK

Download         Length: 285 bp

>AT91857 NZ_CP025737:32-316 [Salmonella enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB V0SVC8

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0Y880

References