Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1876129..1876274 Replicon chromosome
Accession NZ_CP025684
Organism Klebsiella pneumoniae strain L5-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1876165..1876267 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1876129..1876274 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0067_RS09935 1871259..1873319 + 2061 WP_004151449.1 oligopeptidase B -
C0067_RS09940 1873323..1873982 - 660 WP_002911407.1 exodeoxyribonuclease X -
C0067_RS09945 1874061..1874291 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C0067_RS09950 1874404..1874778 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C0067_RS09955 1874782..1875651 + 870 WP_115658448.1 copper homeostasis membrane protein CopD -
C0067_RS09960 1875668..1876006 + 339 WP_002911404.1 YebY family protein -
- 1876129..1876274 - 146 - - Antitoxin
- 1876165..1876267 + 103 - - Toxin
C0067_RS26800 1876642..1876785 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C0067_RS09970 1876890..1877858 - 969 WP_004151446.1 VirK/YbjX family protein -
C0067_RS09975 1878015..1878668 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
C0067_RS09980 1878665..1878856 - 192 WP_002911395.1 YebW family protein -
C0067_RS09985 1878954..1879193 - 240 WP_002911393.1 YebV family protein -
C0067_RS09990 1879309..1880742 - 1434 WP_128206428.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T91719 NZ_CP025684:1876165-1876267 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT91719 NZ_CP025684:c1876274-1876129 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References