Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2996820..2997348 Replicon chromosome
Accession NZ_CP025682
Organism Azoarcus pumilus strain SY39

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag C0099_RS14690 Protein ID WP_102248121.1
Coordinates 2997082..2997348 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag C0099_RS14685 Protein ID WP_102248120.1
Coordinates 2996820..2997095 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0099_RS16070 2992382..2992549 + 168 WP_164084949.1 hypothetical protein -
C0099_RS14655 2992581..2992847 - 267 WP_102248114.1 BrnA antitoxin family protein -
C0099_RS14660 2992819..2993130 - 312 WP_102248115.1 BrnT family toxin -
C0099_RS14665 2993244..2994110 - 867 WP_102248116.1 alpha/beta hydrolase -
C0099_RS14670 2994175..2995278 - 1104 WP_102248117.1 putative sulfate/molybdate transporter -
C0099_RS14675 2995287..2996000 - 714 WP_102248118.1 phosphate ABC transporter ATP-binding protein -
C0099_RS14680 2996008..2996709 - 702 WP_102248119.1 ABC transporter permease -
C0099_RS14685 2996820..2997095 - 276 WP_102248120.1 CopG family transcriptional regulator Antitoxin
C0099_RS14690 2997082..2997348 - 267 WP_102248121.1 BrnT family toxin Toxin
C0099_RS14695 2997388..2998467 - 1080 WP_199797627.1 low-specificity L-threonine aldolase -
C0099_RS14700 2998558..2999769 - 1212 WP_199797628.1 CoA transferase -
C0099_RS14705 2999769..3000542 - 774 WP_102248123.1 enoyl-CoA hydratase/isomerase family protein -
C0099_RS14710 3000594..3001877 - 1284 WP_102248124.1 TRAP transporter large permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10325.68 Da        Isoelectric Point: 10.0392

>T91712 WP_102248121.1 NZ_CP025682:c2997348-2997082 [Azoarcus pumilus]
MYAFEFDENKSRANFTKHGVDFSVARRLWNDPDFVEIAARSTDEPRSLVIGRIDGKCWSAVITYRGRTVRIISVRRSRPR
EVELYESK

Download         Length: 267 bp

>T91712 NZ_CP025682:c2997348-2997082 [Azoarcus pumilus]
ATGTACGCGTTCGAGTTCGACGAGAACAAGAGCCGGGCCAACTTCACCAAGCACGGTGTCGATTTCAGCGTTGCCCGGCG
TTTGTGGAACGACCCTGATTTTGTCGAGATCGCGGCGCGCTCCACGGACGAGCCGCGCTCGCTCGTCATCGGACGAATCG
ACGGCAAGTGCTGGTCGGCAGTGATTACCTATCGCGGGCGGACGGTCCGGATCATTTCGGTGCGGCGATCCCGTCCGCGG
GAGGTGGAACTCTATGAAAGCAAATAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10456.63 Da        Isoelectric Point: 5.7101

>AT91712 WP_102248120.1 NZ_CP025682:c2997095-2996820 [Azoarcus pumilus]
MKANKFDKKFDDGNDDVIDDLDLSSARRPNQLQKRVNVDFPTWMIESLDREASRIGVTRQSIIKVWLAERLEQLSSSATS
HEGQSAIRHQD

Download         Length: 276 bp

>AT91712 NZ_CP025682:c2997095-2996820 [Azoarcus pumilus]
ATGAAAGCAAATAAGTTTGACAAGAAGTTCGACGACGGGAATGACGATGTGATCGACGATCTGGACCTGTCGAGCGCACG
TCGTCCGAATCAGCTCCAGAAGCGGGTGAATGTCGATTTCCCCACGTGGATGATCGAATCGCTCGACCGCGAAGCGAGCC
GCATCGGAGTCACCCGCCAATCGATCATCAAGGTCTGGTTGGCCGAGCGCCTGGAGCAGCTGTCGAGTTCCGCAACGTCG
CACGAAGGACAATCCGCGATCCGGCATCAGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References