91710

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 2064863..2065559 Replicon chromosome
Accession NZ_CP025682
Organism Azoarcus pumilus strain SY39

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag C0099_RS09945 Protein ID WP_102247287.1
Coordinates 2064863..2065240 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag C0099_RS09950 Protein ID WP_102247288.1
Coordinates 2065221..2065559 (+) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0099_RS09915 2059898..2060827 + 930 WP_164084901.1 LysR family transcriptional regulator -
C0099_RS09920 2060933..2061574 - 642 WP_199797593.1 DUF2959 domain-containing protein -
C0099_RS09925 2061793..2062647 - 855 WP_102247283.1 serine protein kinase RIO -
C0099_RS09930 2062644..2062886 - 243 WP_102247284.1 VF530 family protein -
C0099_RS09935 2063727..2064056 + 330 WP_102247285.1 type II toxin-antitoxin system PrlF family antitoxin -
C0099_RS09940 2064053..2064568 + 516 WP_102247286.1 type II toxin-antitoxin system YhaV family toxin -
C0099_RS15875 2064518..2064685 - 168 Protein_1946 HNH endonuclease -
C0099_RS09945 2064863..2065240 + 378 WP_102247287.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C0099_RS09950 2065221..2065559 + 339 WP_102247288.1 helix-turn-helix domain-containing protein Antitoxin
C0099_RS09955 2065738..2066691 - 954 WP_102247289.1 HNH endonuclease -
C0099_RS09960 2066695..2067078 - 384 WP_102247290.1 HIT domain-containing protein -
C0099_RS09970 2067697..2069253 + 1557 WP_102247291.1 malonate decarboxylase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(18-97)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13789.90 Da        Isoelectric Point: 9.9259

>T91710 WP_102247287.1 NZ_CP025682:2064863-2065240 [Azoarcus pumilus]
MPEKEKPLQWIGSSYKDLLALPPDVRRRFGYALSLAQMGDQDDAAKALKGFGGAGVLEVVEDNVGGTYRAVYTVKFAESV
FVLHCFQKKSKSGIATPKADMDIIRTRLKVAESLAQELRNAKTNR

Download         Length: 378 bp

>T91710 NZ_CP025682:2064863-2065240 [Azoarcus pumilus]
ATGCCCGAAAAGGAAAAACCGCTCCAATGGATCGGAAGCAGCTACAAGGATCTGTTGGCGCTGCCCCCTGACGTGCGTCG
ACGTTTCGGTTACGCACTGTCACTGGCTCAGATGGGCGACCAGGACGACGCTGCGAAGGCGCTCAAGGGCTTCGGCGGTG
CAGGCGTGCTGGAAGTCGTCGAAGACAATGTCGGCGGCACCTACCGGGCGGTCTACACGGTAAAGTTTGCGGAATCAGTG
TTCGTGCTGCACTGCTTTCAGAAGAAGAGCAAGAGCGGGATCGCCACGCCCAAAGCGGACATGGACATCATTCGTACTCG
GCTGAAGGTGGCCGAGTCGTTGGCACAGGAGCTACGAAATGCAAAGACGAATCGTTGA

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12324.48 Da        Isoelectric Point: 10.5376

>AT91710 WP_102247288.1 NZ_CP025682:2065221-2065559 [Azoarcus pumilus]
MQRRIVDGIEVQHSSGNVFADLKLPDAEKLKVKTGLVVEIRKAIRALGLTQQAAAKRMGIPQPKVSGMMRGDFTNLSERK
LMDCLNRLGYDIEIKVRPAAEPVGHLTLATTT

Download         Length: 339 bp

>AT91710 NZ_CP025682:2065221-2065559 [Azoarcus pumilus]
ATGCAAAGACGAATCGTTGACGGCATCGAGGTTCAACACAGCTCGGGCAACGTGTTCGCCGACCTGAAGCTGCCCGATGC
CGAGAAACTGAAAGTCAAGACCGGGCTGGTGGTCGAGATCAGGAAGGCGATACGCGCTCTGGGGCTGACACAACAAGCGG
CGGCCAAGCGCATGGGCATCCCGCAACCGAAGGTATCGGGCATGATGCGAGGTGACTTTACGAATCTGTCCGAGCGCAAG
CTGATGGACTGTTTGAACCGTCTTGGCTACGACATCGAAATCAAGGTGCGGCCTGCAGCCGAGCCAGTCGGGCATCTGAC
GCTCGCAACCACCACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References