91702

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 174483..175156 Replicon chromosome
Accession NZ_CP025682
Organism Azoarcus pumilus strain SY39

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C0099_RS00895 Protein ID WP_102245690.1
Coordinates 174483..174905 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C0099_RS00900 Protein ID WP_102245691.1
Coordinates 174902..175156 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0099_RS00850 169854..170066 - 213 WP_102245682.1 hypothetical protein -
C0099_RS00855 170138..171385 - 1248 WP_102245683.1 uracil-xanthine permease family protein -
C0099_RS00860 171554..172186 - 633 WP_102248328.1 uracil phosphoribosyltransferase -
C0099_RS00865 172409..172660 + 252 WP_102245684.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
C0099_RS00870 172657..172911 + 255 WP_102245685.1 Txe/YoeB family addiction module toxin -
C0099_RS00875 173145..173528 - 384 WP_199797637.1 HigA family addiction module antidote protein -
C0099_RS00880 173438..173716 - 279 WP_102245687.1 type II toxin-antitoxin system RelE/ParE family toxin -
C0099_RS00885 173769..174164 - 396 WP_102245688.1 type II toxin-antitoxin system VapC family toxin -
C0099_RS00890 174161..174406 - 246 WP_102245689.1 Arc family DNA-binding protein -
C0099_RS00895 174483..174905 - 423 WP_102245690.1 type II toxin-antitoxin system VapC family toxin Toxin
C0099_RS00900 174902..175156 - 255 WP_102245691.1 plasmid stabilization protein Antitoxin
C0099_RS00905 175459..177048 - 1590 WP_102245692.1 SEC-C domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14843.10 Da        Isoelectric Point: 5.1283

>T91702 WP_102245690.1 NZ_CP025682:c174905-174483 [Azoarcus pumilus]
MIVLDTNVVSEAMKAAPNATVLAWLDEQAAETLYLSSVTLAELLFGIGAPPSGRRKDALKQTLDGLLVLFADRVLPFDTD
AARHYAELAVSARAAGKGFPTPDGYIAAIAKARGFTVATRDVAPFQAAGLKVINPWEAMQ

Download         Length: 423 bp

>T91702 NZ_CP025682:c174905-174483 [Azoarcus pumilus]
ATGATCGTCCTGGATACCAATGTCGTTTCCGAGGCGATGAAAGCCGCGCCGAACGCCACCGTGCTGGCGTGGTTGGATGA
GCAGGCGGCCGAAACCCTTTACCTTTCCAGCGTCACGCTTGCCGAACTGCTGTTCGGCATCGGTGCCCCGCCATCCGGCC
GGCGCAAGGATGCGCTGAAGCAAACGCTGGATGGCCTTCTGGTGCTGTTCGCGGATCGCGTGCTCCCCTTTGACACCGAC
GCAGCCCGGCACTACGCCGAGCTGGCCGTTTCCGCCCGAGCGGCCGGCAAGGGCTTCCCCACACCCGACGGCTATATCGC
CGCCATCGCGAAGGCTCGCGGTTTCACCGTCGCCACGCGCGACGTTGCGCCATTCCAGGCGGCGGGCCTCAAGGTCATCA
ATCCGTGGGAGGCCATGCAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9343.59 Da        Isoelectric Point: 6.4743

>AT91702 WP_102245691.1 NZ_CP025682:c175156-174902 [Azoarcus pumilus]
MATVTVRNLPDEVHRALRVRAATHGRSTEAEIREILESTVRPPERLRLGSALAELGRRVGLTDDDIAAIEKVRDKTPTEP
VSFE

Download         Length: 255 bp

>AT91702 NZ_CP025682:c175156-174902 [Azoarcus pumilus]
ATGGCGACAGTCACCGTCAGAAATCTGCCGGACGAGGTGCATCGCGCGCTTCGTGTGCGCGCAGCGACGCACGGCCGCAG
CACCGAGGCCGAAATCCGCGAGATTCTCGAATCGACCGTTCGCCCGCCGGAGCGGCTTCGCTTGGGCTCGGCTCTCGCCG
AACTGGGCCGCCGCGTCGGGCTGACCGATGACGACATCGCGGCCATCGAGAAGGTGCGCGACAAGACCCCGACCGAGCCT
GTGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References