Detailed information of TA system TA091616

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 483928..484564
• Replicon: chromosome
• Accession: NZ_CP025618
• Organism: Acinetobacter schindleri strain SGAir0122

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: C0119_RS02380
• Protein ID: WP_048881826.1
• Coordinates: 484178..484564 (+)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: I4ZVX5
• Locus tag: C0119_RS02375
• Protein ID: WP_008302635.1
• Coordinates: 483928..484185 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C0119_RS02355	479399..480406	+	1008	WP_004809777.1	DNA-directed RNA polymerase subunit alpha	-
C0119_RS02360	480425..480790	+	366	WP_004786886.1	50S ribosomal protein L17	-
C0119_RS02365	481010..482515	+	1506	WP_108675545.1	NAD(P)/FAD-dependent oxidoreductase	-
C0119_RS02370	482579..483751	-	1173	WP_108675544.1	acyl-CoA dehydrogenase family protein	-
C0119_RS02375	483928..484185	+	258	WP_008302635.1	succinate dehydrogenase assembly factor 2	Antitoxin
C0119_RS02380	484178..484564	+	387	WP_048881826.1	hypothetical protein	Toxin
C0119_RS02385	485106..486146	+	1041	WP_108675543.1	hypothetical protein	-
C0119_RS02390	486212..486784	+	573	WP_034592075.1	rhombosortase	-
C0119_RS02395	486961..489156	+	2196	WP_008302626.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15522.54 Da
• Isoelectric Point: 9.6431

>T91616 WP_048881826.1 NZ_CP025618:484178-484564 [Acinetobacter schindleri]
MDNRCYQLKRSLLALAFQFFIFIVLMFVMYQLLPLWLWGICLVAGLIIYHLFYRKRPQIAQFEYLDGREWTITHHDQRIQ
RAQISHVIDHQAYLVVYFQHAKVPPLLIWCDQLPTQQWKSLKVLTKMI

Nucleotide

• Length: 387 bp

>T91616 NZ_CP025618:484178-484564 [Acinetobacter schindleri]
ATGGATAATCGTTGTTATCAGCTGAAACGCAGCCTGCTTGCACTTGCGTTTCAGTTTTTCATTTTTATTGTGTTGATGTT
TGTGATGTACCAGTTATTGCCCTTATGGCTATGGGGAATCTGTCTGGTTGCAGGACTGATCATCTATCATCTGTTTTATC
GCAAGCGTCCGCAGATCGCCCAGTTTGAATATTTGGATGGTCGGGAATGGACCATTACCCATCATGATCAGCGCATACAG
CGTGCCCAGATCAGTCATGTGATTGATCACCAAGCTTATCTGGTGGTGTATTTTCAGCATGCCAAAGTACCGCCATTGCT
GATCTGGTGTGACCAGTTACCAACACAACAATGGAAGTCATTGAAAGTCCTTACGAAAATGATCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10254.70 Da
• Isoelectric Point: 4.4898

>AT91616 WP_008302635.1 NZ_CP025618:483928-484185 [Acinetobacter schindleri]
MTEDISLEERKVIYRARRGLKELDVYFDPYVKNCYLTADPFEKEMFAELVAQEDPDLLDWFMEVSEPPRPELREFINKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT91616 NZ_CP025618:483928-484185 [Acinetobacter schindleri]
ATGACTGAAGACATCAGCCTGGAAGAGCGTAAAGTGATTTACCGCGCACGTCGTGGTCTTAAAGAGTTGGATGTGTATTT
TGATCCCTATGTCAAAAACTGCTATTTGACAGCAGACCCATTTGAAAAAGAAATGTTTGCTGAACTCGTAGCGCAAGAAG
ACCCGGACCTGCTGGACTGGTTTATGGAAGTATCCGAACCGCCACGCCCTGAATTACGTGAGTTTATTAACAAGCTTAAA
CACTACGTTCATGGATAA

Structures

Antitoxin

• AlphaFold DB: A0A1P8PMS5