Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 50054..50712 Replicon chromosome
Accession NZ_CP025611
Organism Niveispirillum cyanobacteriorum strain TH16

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C0V82_RS00205 Protein ID WP_102110612.1
Coordinates 50311..50712 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C0V82_RS00200 Protein ID WP_102110611.1
Coordinates 50054..50314 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0V82_RS00185 45533..48649 - 3117 WP_102110609.1 bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA -
C0V82_RS00190 48782..49270 + 489 WP_102110610.1 Lrp/AsnC ligand binding domain-containing protein -
C0V82_RS27215 49385..49888 + 504 WP_199772438.1 helix-turn-helix transcriptional regulator -
C0V82_RS00200 50054..50314 + 261 WP_102110611.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
C0V82_RS00205 50311..50712 + 402 WP_102110612.1 type II toxin-antitoxin system VapC family toxin Toxin
C0V82_RS00210 50942..51310 + 369 WP_102110613.1 hypothetical protein -
C0V82_RS00215 51341..51667 + 327 WP_102110614.1 DUF2200 domain-containing protein -
C0V82_RS00220 51678..52427 - 750 WP_102110615.1 aminotransferase class IV -
C0V82_RS00225 52424..53890 - 1467 WP_102110616.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-123)

Antitoxin

SpoVT-AbrB domain

(8-49)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14685.07 Da        Isoelectric Point: 6.7509

>T91607 WP_102110612.1 NZ_CP025611:50311-50712 [Niveispirillum cyanobacteriorum]
MTRHMLDTNSVNHLLREHPVVVRRVVAAPMASLCLSAVTEAELRYGLAKRPEATRLHRVVGELLLRLDVLPWESEVARTY
GALRAGMERQGKVLAPLDLMIAAHAIATGCTLVSNDQAFAHLPDLDLEDWTIG

Download         Length: 402 bp

>T91607 NZ_CP025611:50311-50712 [Niveispirillum cyanobacteriorum]
TTGACTCGCCATATGCTGGACACCAACAGCGTCAACCACCTGCTGCGGGAGCATCCGGTGGTGGTCCGGCGCGTTGTGGC
AGCCCCCATGGCCTCGCTGTGCCTTTCTGCCGTCACCGAAGCGGAGTTGCGCTATGGGCTGGCCAAACGACCTGAAGCGA
CCCGACTGCACCGCGTCGTGGGTGAGTTGCTGTTGCGCCTGGATGTCCTGCCCTGGGAGAGTGAGGTGGCGCGGACCTAT
GGCGCGTTACGGGCGGGGATGGAGCGGCAGGGCAAGGTTCTGGCACCGCTGGACCTGATGATCGCCGCACATGCCATCGC
CACAGGCTGCACCCTGGTCAGCAACGATCAGGCATTCGCGCATCTGCCCGATCTTGACCTGGAGGATTGGACCATCGGGT
GA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9448.56 Da        Isoelectric Point: 4.7242

>AT91607 WP_102110611.1 NZ_CP025611:50054-50314 [Niveispirillum cyanobacteriorum]
MSQTAKLFTNGRSQAVRLPAAFRFDAKEVFIRQDPVTGDVILSRKPADWAGFLDLLKGTDVPDDFLGAGDRQQDAHARDP
FEGLDG

Download         Length: 261 bp

>AT91607 NZ_CP025611:50054-50314 [Niveispirillum cyanobacteriorum]
ATGAGCCAAACAGCAAAACTGTTCACCAATGGCAGGAGCCAAGCAGTTCGGCTCCCGGCGGCGTTTCGGTTCGATGCCAA
GGAAGTGTTCATCCGGCAGGACCCGGTGACGGGTGACGTGATCCTGTCACGCAAGCCGGCGGATTGGGCAGGATTCCTGG
ACCTGCTTAAAGGGACCGACGTTCCGGATGATTTCCTGGGAGCCGGTGACCGCCAACAGGATGCTCATGCCCGAGACCCG
TTCGAGGGATTGGACGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References