Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 113921..114574 Replicon plasmid pCBA4604-01
Accession NZ_CP025584
Organism Paracoccus jeotgali strain CBA4604

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CYR75_RS15580 Protein ID WP_101501173.1
Coordinates 114170..114574 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CYR75_RS15575 Protein ID WP_101501172.1
Coordinates 113921..114169 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYR75_RS15555 109660..110676 - 1017 WP_101501169.1 TAXI family TRAP transporter solute-binding subunit -
CYR75_RS15560 110785..111693 - 909 WP_101501170.1 LysR family transcriptional regulator -
CYR75_RS15565 111864..112820 + 957 WP_101501202.1 membrane dipeptidase -
CYR75_RS15570 112837..113190 + 354 WP_101501171.1 RidA family protein -
CYR75_RS15575 113921..114169 + 249 WP_101501172.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CYR75_RS15580 114170..114574 + 405 WP_101501173.1 type II toxin-antitoxin system VapC family toxin Toxin
CYR75_RS15585 114845..115981 - 1137 WP_101501174.1 ParB N-terminal domain-containing protein -
CYR75_RS15590 115978..117282 - 1305 WP_101501203.1 AAA family ATPase -
CYR75_RS15595 117794..118486 + 693 WP_101501175.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..149225 149225


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-56)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14773.86 Da        Isoelectric Point: 5.1552

>T90627 WP_101501173.1 NZ_CP025584:114170-114574 [Paracoccus jeotgali]
MLILDTNVVSALRRPERAPQVAAWLAQQQEDQLYLSVVTLGEIERGIARQDKLDPSFATDLRAWLARTEQLFGDRLLPVD
ARVARIWGELSARLGHSGADLLIAATALRHDAVVATRNVDDFTPTGCLITNPFA

Download         Length: 405 bp

>T90627 NZ_CP025584:114170-114574 [Paracoccus jeotgali]
ATGCTGATCCTCGACACCAATGTCGTTTCTGCACTGCGGCGTCCCGAGCGCGCGCCTCAGGTCGCCGCATGGCTCGCGCA
GCAGCAAGAGGATCAGCTTTATCTGTCCGTCGTGACCTTGGGCGAGATCGAGCGCGGCATTGCCCGCCAGGATAAGCTTG
ATCCGAGCTTTGCAACGGATCTGCGCGCATGGCTTGCGCGAACGGAGCAGCTATTCGGTGATCGCCTGCTTCCGGTCGAT
GCGCGAGTTGCGCGGATCTGGGGAGAGCTGTCGGCCCGGCTTGGCCATAGCGGGGCCGACTTGCTGATCGCAGCCACGGC
ACTTCGCCACGACGCCGTCGTGGCGACCAGGAACGTCGATGATTTCACCCCGACCGGGTGCCTGATCACCAACCCTTTCG
CCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8816.06 Da        Isoelectric Point: 9.2340

>AT90627 WP_101501172.1 NZ_CP025584:113921-114169 [Paracoccus jeotgali]
MWSLQDAKNRFSAVVAAALAGEPQEVTRRGKPAVVVLSAAEYARMLDAARAARGSFARHLLAQPCGELDESRPGVHPRDV
AF

Download         Length: 249 bp

>AT90627 NZ_CP025584:113921-114169 [Paracoccus jeotgali]
ATGTGGAGTCTTCAGGACGCAAAGAACCGCTTTTCGGCGGTTGTTGCCGCGGCGCTCGCCGGCGAGCCGCAAGAGGTAAC
TCGTCGCGGCAAGCCTGCTGTCGTCGTCCTCTCTGCGGCTGAATACGCTCGCATGCTGGACGCAGCGCGGGCGGCGCGTG
GCAGCTTTGCCCGGCATCTCTTGGCGCAGCCCTGCGGAGAACTCGATGAAAGTCGCCCTGGTGTGCATCCGCGCGATGTC
GCGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References