Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
| Location | 5304464..5305284 | Replicon | chromosome |
| Accession | NZ_CP025573 | ||
| Organism | Escherichia coli strain E-1246 | ||
Toxin (Protein)
| Gene name | yjhX | Uniprot ID | A0A0V9MKL8 |
| Locus tag | CY655_RS26180 | Protein ID | WP_001550554.1 |
| Coordinates | 5305027..5305284 (-) | Length | 86 a.a. |
Antitoxin (Protein)
| Gene name | yjhQ | Uniprot ID | - |
| Locus tag | CY655_RS26175 | Protein ID | WP_001519303.1 |
| Coordinates | 5304464..5305015 (-) | Length | 184 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CY655_RS26150 | 5300159..5301472 | - | 1314 | WP_001519300.1 | galactitol-specific PTS transporter subunit IIC | - |
| CY655_RS26155 | 5301484..5301762 | - | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB | - |
| CY655_RS26160 | 5301759..5302880 | - | 1122 | WP_000010833.1 | M42 family metallopeptidase | - |
| CY655_RS27950 | 5303125..5303241 | - | 117 | Protein_4985 | VOC family protein | - |
| CY655_RS26165 | 5303279..5303539 | - | 261 | WP_000084876.1 | hypothetical protein | - |
| CY655_RS26170 | 5303666..5304214 | - | 549 | WP_001519301.1 | hypothetical protein | - |
| CY655_RS27955 | 5304251..5304412 | - | 162 | WP_001519302.1 | hypothetical protein | - |
| CY655_RS26175 | 5304464..5305015 | - | 552 | WP_001519303.1 | N-acetyltransferase | Antitoxin |
| CY655_RS26180 | 5305027..5305284 | - | 258 | WP_001550554.1 | hypothetical protein | Toxin |
| CY655_RS26185 | 5305661..5305960 | - | 300 | WP_127904481.1 | GNAT family N-acetyltransferase | - |
| CY655_RS26190 | 5306023..5306547 | + | 525 | Protein_4992 | DNA helicase | - |
| CY655_RS26200 | 5306599..5307303 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| CY655_RS26205 | 5307372..5308523 | + | 1152 | WP_001551998.1 | 2-hydroxyacyl-CoA dehydratase subunit D | - |
| CY655_RS26210 | 5308533..5309300 | + | 768 | WP_001297641.1 | hypothetical protein | - |
| CY655_RS26215 | 5309297..5309554 | + | 258 | WP_000666413.1 | DUF3343 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 5306599..5307303 | 704 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9744.33 Da Isoelectric Point: 11.0090
>T90590 WP_001550554.1 NZ_CP025573:c5305284-5305027 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKPVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKPVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
>T90590 NZ_CP025573:c5305284-5305027 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGCCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGCCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
Antitoxin
Download Length: 184 a.a. Molecular weight: 20463.61 Da Isoelectric Point: 6.8758
>AT90590 WP_001519303.1 NZ_CP025573:c5305015-5304464 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCAQALMKPEHWRE
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCAQALMKPEHWRE
Download Length: 552 bp
>AT90590 NZ_CP025573:c5305015-5304464 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCGACCTTCAAAGGAGAAATGGATTCACCGCTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCGCAGGCCCTGATGAAACCGGAGCACTGGCGTGAATAA
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCGACCTTCAAAGGAGAAATGGATTCACCGCTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCGCAGGCCCTGATGAAACCGGAGCACTGGCGTGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|