Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 12876..13398 Replicon plasmid p2PIR00532
Accession NZ_CP025558
Organism Salmonella enterica subsp. enterica serovar Enteritidis strain PIR00532

Toxin (Protein)


Gene name relE Uniprot ID A9LK42
Locus tag C0Z07_RS00485 Protein ID WP_000220562.1
Coordinates 13117..13398 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3CAG1
Locus tag C0Z07_RS00480 Protein ID WP_000121743.1
Coordinates 12876..13127 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C0Z07_RS00445 7955..8185 + 231 WP_000051064.1 partitioning protein -
C0Z07_RS00450 8202..8513 + 312 WP_000360321.1 hypothetical protein -
C0Z07_RS00455 8551..9171 + 621 WP_012477163.1 hypothetical protein -
C0Z07_RS00460 9196..9831 + 636 WP_012477164.1 hypothetical protein -
C0Z07_RS00465 9862..10284 - 423 WP_001467132.1 DNA distortion polypeptide 3 -
C0Z07_RS00470 10321..10767 - 447 WP_001074382.1 hypothetical protein -
C0Z07_RS00475 10807..11643 - 837 WP_001802123.1 replication initiation protein -
C0Z07_RS00480 12876..13127 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin
C0Z07_RS00485 13117..13398 + 282 WP_000220562.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C0Z07_RS00490 13544..13867 + 324 WP_001181905.1 hypothetical protein -
C0Z07_RS00495 13915..14160 + 246 WP_000356542.1 hypothetical protein -
C0Z07_RS00500 14150..14365 + 216 WP_001180117.1 hypothetical protein -
C0Z07_RS00505 14458..14787 + 330 WP_000866654.1 hypothetical protein -
C0Z07_RS00510 14829..15008 + 180 WP_000439079.1 hypothetical protein -
C0Z07_RS24675 15078..15227 + 150 WP_000003880.1 hypothetical protein -
C0Z07_RS00520 15240..15512 + 273 WP_000160399.1 hypothetical protein -
C0Z07_RS24680 15769..15843 + 75 Protein_26 DNA distortion polypeptide 3 -
C0Z07_RS00530 15838..16383 + 546 WP_020801480.1 hypothetical protein -
C0Z07_RS00535 16386..17552 + 1167 WP_012477147.1 relaxase/mobilization nuclease domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..30098 30098


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(91-151)

Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T90557 WP_000220562.1 NZ_CP025558:13117-13398 [Salmonella enterica subsp. enterica serovar Enteritidis]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T90557 NZ_CP025558:13117-13398 [Salmonella enterica subsp. enterica serovar Enteritidis]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 10784.64 Da        Isoelectric Point: 12.7191

>AT90557 WP_000121743.1 NZ_CP025558:12876-13127 [Salmonella enterica subsp. enterica serovar Enteritidis]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Download         Length: 252 bp

>AT90557 NZ_CP025558:12876-13127 [Salmonella enterica subsp. enterica serovar Enteritidis]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A9LK42

Antitoxin

Source ID Structure
AlphaFold DB A0A3S5I301

References