Detailed information of TA system TA090554

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 33856..34481
• Replicon: plasmid pPIR00538
• Accession: NZ_CP025556
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium strain PIR00538

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: C0Z08_RS25250
• Protein ID: WP_000911322.1
• Coordinates: 33856..34254 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: C0Z08_RS25255
• Protein ID: WP_000450265.1
• Coordinates: 34254..34481 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C0Z08_RS25235	30047..30541	+	495	WP_010999946.1	entry exclusion protein	-
C0Z08_RS25240	30577..31308	+	732	WP_000782438.1	complement resistance protein TraT	-
C0Z08_RS25245	31685..33847	+	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
C0Z08_RS25250	33856..34254	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
C0Z08_RS25255	34254..34481	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93832	93832

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (7-112)

Antitoxin

• Predicted DNA-binding protein, ribbon-helix-helix domain (16-47)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T90554 WP_000911322.1 NZ_CP025556:c34254-33856 [Salmonella enterica subsp. enterica serovar Typhimurium]
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Nucleotide

• Length: 399 bp

>T90554 NZ_CP025556:c34254-33856 [Salmonella enterica subsp. enterica serovar Typhimurium]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT90554 WP_000450265.1 NZ_CP025556:c34481-34254 [Salmonella enterica subsp. enterica serovar Typhimurium]
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Nucleotide

• Length: 228 bp

>AT90554 NZ_CP025556:c34481-34254 [Salmonella enterica subsp. enterica serovar Typhimurium]
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