Detailed information of TA system TA090546

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 5868685..5869207
• Replicon: chromosome
• Accession: NZ_CP025542
• Organism: Pseudomonas fluorescens strain 2P24

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C0J56_RS26530
• Protein ID: WP_134926001.1
• Coordinates: 5868914..5869207 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C0J56_RS26525
• Protein ID: WP_134926000.1
• Coordinates: 5868685..5868924 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C0J56_RS26495	5863816..5864517	-	702	WP_134925996.1	DUF1190 domain-containing protein	-
C0J56_RS26500	5864537..5864965	-	429	WP_134925997.1	DUF350 domain-containing protein	-
C0J56_RS26505	5864981..5865643	-	663	WP_134925998.1	DUF2491 family protein	-
C0J56_RS26510	5865630..5866664	-	1035	WP_134925999.1	NAD-binding protein	-
C0J56_RS26515	5867068..5867766	-	699	WP_003185899.1	PspA/IM30 family protein	-
C0J56_RS26520	5867789..5868370	-	582	WP_092258175.1	YjfI family protein	-
C0J56_RS26525	5868685..5868924	+	240	WP_134926000.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
C0J56_RS26530	5868914..5869207	+	294	WP_134926001.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C0J56_RS26535	5869267..5870100	-	834	WP_134926002.1	DUF2135 domain-containing protein	-
C0J56_RS26540	5870104..5871723	-	1620	WP_134926003.1	DUF2300 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-81)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-62)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11546.37 Da
• Isoelectric Point: 9.9386

>T90546 WP_134926001.1 NZ_CP025542:5868914-5869207 [Pseudomonas fluorescens]
MTYSLEFDRRALKEWNKLGETLRQQFKKKLIEILENPRVEANRLRQLPDCYKLKLRSAGYRLIYQVIDQEVVVFVVAIGK
REREAVYQDAQERISSG

Nucleotide

• Length: 294 bp

>T90546 NZ_CP025542:5868914-5869207 [Pseudomonas fluorescens]
ATGACCTATAGCCTTGAATTTGATCGACGCGCATTGAAGGAGTGGAACAAGCTAGGCGAAACACTGCGACAGCAGTTCAA
AAAGAAGCTCATCGAGATTCTTGAAAACCCCCGCGTCGAAGCCAACCGACTCCGACAACTCCCCGACTGCTACAAGTTGA
AACTGCGCAGCGCCGGGTATCGCCTGATCTATCAGGTCATTGATCAAGAAGTCGTGGTGTTCGTCGTTGCGATAGGAAAA
CGCGAGCGTGAAGCGGTTTATCAGGATGCGCAGGAGCGCATCTCATCCGGCTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8883.22 Da
• Isoelectric Point: 4.6017

>AT90546 WP_134926000.1 NZ_CP025542:5868685-5868924 [Pseudomonas fluorescens]
MASINIRIDDDLKQRSFAELEKLGVTPSELLRQTLQYVAERGKLPFKTALISEEDEALIAVVTERLASPQRVKVSLDDL

Nucleotide

• Length: 240 bp

>AT90546 NZ_CP025542:5868685-5868924 [Pseudomonas fluorescens]
ATGGCTTCCATCAACATCCGCATTGACGATGACCTTAAGCAGCGGTCATTTGCCGAACTGGAAAAGCTCGGGGTCACGCC
TTCCGAACTGCTACGCCAGACACTTCAATACGTGGCGGAGCGAGGCAAATTGCCTTTCAAGACAGCATTAATCAGCGAAG
AAGATGAAGCGCTCATTGCAGTGGTTACGGAACGCCTCGCCAGCCCTCAACGAGTAAAGGTCAGCCTGGATGACCTATAG