Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/Phd(antitoxin) |
| Location | 2685234..2685781 | Replicon | chromosome |
| Accession | NZ_CP025537 | ||
| Organism | Vibrio harveyi strain 345 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A454B353 |
| Locus tag | CU052_RS12730 | Protein ID | WP_005445657.1 |
| Coordinates | 2685479..2685781 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | CU052_RS12725 | Protein ID | WP_101904706.1 |
| Coordinates | 2685234..2685491 (+) | Length | 86 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CU052_RS12665 | 2680708..2681139 | + | 432 | WP_101904700.1 | hypothetical protein | - |
| CU052_RS12670 | 2681154..2681246 | + | 93 | WP_199828246.1 | DUF3265 domain-containing protein | - |
| CU052_RS12675 | 2681651..2681776 | + | 126 | WP_101905108.1 | DUF3265 domain-containing protein | - |
| CU052_RS12680 | 2682231..2682323 | + | 93 | WP_079880921.1 | DUF3265 domain-containing protein | - |
| CU052_RS12685 | 2682352..2682723 | + | 372 | WP_045381734.1 | hypothetical protein | - |
| CU052_RS12690 | 2682750..2682839 | + | 90 | WP_199828288.1 | DUF3265 domain-containing protein | - |
| CU052_RS12700 | 2683329..2683460 | + | 132 | WP_017821410.1 | DUF3265 domain-containing protein | - |
| CU052_RS12705 | 2683479..2683874 | - | 396 | WP_101904703.1 | leucine-rich repeat protein | - |
| CU052_RS12710 | 2684193..2684627 | + | 435 | WP_101904704.1 | hypothetical protein | - |
| CU052_RS12715 | 2684606..2685040 | + | 435 | WP_101904705.1 | hypothetical protein | - |
| CU052_RS12720 | 2685051..2685152 | + | 102 | WP_100216259.1 | DUF3265 domain-containing protein | - |
| CU052_RS12725 | 2685234..2685491 | + | 258 | WP_101904706.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| CU052_RS12730 | 2685479..2685781 | + | 303 | WP_005445657.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| CU052_RS12735 | 2685825..2685977 | - | 153 | Protein_2312 | IS30 family transposase | - |
| CU052_RS12740 | 2686070..2686297 | + | 228 | WP_017190347.1 | type II toxin-antitoxin system YafO family toxin | - |
| CU052_RS12745 | 2686306..2686508 | + | 203 | Protein_2314 | hypothetical protein | - |
| CU052_RS12750 | 2686563..2686733 | + | 171 | WP_080573696.1 | DUF3265 domain-containing protein | - |
| CU052_RS12755 | 2686749..2687165 | + | 417 | WP_005445653.1 | hypothetical protein | - |
| CU052_RS12770 | 2688469..2688804 | + | 336 | Protein_2318 | hypothetical protein | - |
| CU052_RS12775 | 2688941..2689342 | + | 402 | WP_005445628.1 | hypothetical protein | - |
| CU052_RS12780 | 2689636..2690739 | - | 1104 | WP_005445626.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2680708..2689342 | 8634 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11681.63 Da Isoelectric Point: 6.9800
>T90526 WP_005445657.1 NZ_CP025537:2685479-2685781 [Vibrio harveyi]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPDLKHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLNKQ
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPDLKHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERDLRKFLLNKQ
Download Length: 303 bp
>T90526 NZ_CP025537:2685479-2685781 [Vibrio harveyi]
ATGGCTGAAATAATCTGGACTGAGCCAGCGTTATCTGACCTCAACGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTCGAACGTTTACAAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGATCTAAAACATTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTTTGTTTGTTATGCGCGCAGAGAGAGATTTGCGTAAGTTCTTGTTAAATAAGCAATAA
ATGGCTGAAATAATCTGGACTGAGCCAGCGTTATCTGACCTCAACGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTGCAAACGATCTTCTCCAAAGTCGAACGTTTACAAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGATCTAAAACATTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTTTGTTTGTTATGCGCGCAGAGAGAGATTTGCGTAAGTTCTTGTTAAATAAGCAATAA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9594.15 Da Isoelectric Point: 7.2772
>AT90526 WP_101904706.1 NZ_CP025537:2685234-2685491 [Vibrio harveyi]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADCKVVSHDEAKGKM
SKWLK
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADCKVVSHDEAKGKM
SKWLK
Download Length: 258 bp
>AT90526 NZ_CP025537:2685234-2685491 [Vibrio harveyi]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATTCTCGCCGATCTCCACGACACCAAAGAACCAGT
GTTAATTACTGAGCATGGTAAGCCATCCGCGTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACTGTAAAGTGGTAAGTCATGATGAAGCCAAGGGCAAAATG
TCAAAATGGCTGAAATAA
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATTCTCGCCGATCTCCACGACACCAAAGAACCAGT
GTTAATTACTGAGCATGGTAAGCCATCCGCGTATCTCGTTGATGTTGATGACTACGAGTTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGACTGTAAAGTGGTAAGTCATGATGAAGCCAAGGGCAAAATG
TCAAAATGGCTGAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|