Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 501847..502637 Replicon plasmid unnamed2
Accession NZ_CP025513
Organism Neorhizobium sp. SOG26

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CYG48_RS18940 Protein ID WP_118852098.1
Coordinates 501847..502344 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag CYG48_RS18945 Protein ID WP_118852099.1
Coordinates 502341..502637 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYG48_RS18915 497287..498258 - 972 WP_118852093.1 ABC transporter ATP-binding protein -
CYG48_RS18920 498264..499163 - 900 WP_118852094.1 ABC transporter permease -
CYG48_RS18925 499160..500134 - 975 WP_118852095.1 ABC transporter permease -
CYG48_RS18930 500344..501237 + 894 WP_118852096.1 LysR family transcriptional regulator -
CYG48_RS18940 501847..502344 - 498 WP_118852098.1 GNAT family N-acetyltransferase Toxin
CYG48_RS18945 502341..502637 - 297 WP_118852099.1 DUF1778 domain-containing protein Antitoxin
CYG48_RS18950 502925..503725 - 801 WP_118852100.1 IclR family transcriptional regulator -
CYG48_RS18955 503796..505112 - 1317 WP_118852101.1 TRAP transporter large permease -
CYG48_RS18960 505137..505685 - 549 WP_118852102.1 TRAP transporter small permease -
CYG48_RS18965 505710..506705 - 996 WP_118852103.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - adeG 1..1172176 1172176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(34-142)

Antitoxin

Vibrio phage ICP1, Orf50

(16-90)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17754.38 Da        Isoelectric Point: 8.0184

>T90466 WP_118852098.1 NZ_CP025513:c502344-501847 [Neorhizobium sp. SOG26]
VILTAPAPLADYHELDEFDSGVPQLDDWLRRRARANQAGGASRTFVACEGNRVIAYYALASGAVKPAEAPGRFRRNMPDP
IPVAVLGRLAIDRSYQSRGLGRALVRDAGLRLLNAAEILGIRGVLVHAISDDARAFYEAVGFLPSPSDPMMLMIGLKDLS
NALNA

Download         Length: 498 bp

>T90466 NZ_CP025513:c502344-501847 [Neorhizobium sp. SOG26]
GTGATACTAACTGCGCCTGCTCCTTTAGCCGATTATCATGAACTGGACGAGTTTGATTCCGGCGTTCCACAACTGGACGA
TTGGTTGCGTCGACGAGCCCGTGCCAATCAGGCAGGTGGGGCATCTCGTACGTTTGTGGCCTGCGAGGGAAATCGCGTTA
TTGCCTACTACGCGCTCGCCTCCGGCGCAGTGAAGCCGGCAGAAGCACCAGGCCGTTTCAGGCGAAACATGCCGGACCCG
ATCCCAGTCGCAGTACTTGGTCGATTGGCTATTGATCGATCTTACCAGAGTCGAGGTCTAGGTCGGGCGTTGGTCCGTGA
TGCAGGCCTGCGCCTGCTTAATGCCGCCGAAATACTTGGTATCCGAGGCGTACTGGTGCATGCCATTTCGGATGATGCAC
GTGCCTTCTATGAAGCTGTCGGATTTCTGCCTTCTCCGTCCGATCCGATGATGCTGATGATCGGATTGAAAGACCTCAGC
AACGCACTGAACGCTTAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11102.62 Da        Isoelectric Point: 8.5687

>AT90466 WP_118852099.1 NZ_CP025513:c502637-502341 [Neorhizobium sp. SOG26]
MPTSHTSKNVNASVPLNIRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTVFTVSPEVYTEYLARLDAPAQ
SNERLKRTMSTKAPWDEA

Download         Length: 297 bp

>AT90466 NZ_CP025513:c502637-502341 [Neorhizobium sp. SOG26]
ATGCCGACGTCACACACCAGCAAGAATGTGAACGCAAGTGTTCCATTGAATATCCGTATCAAGCCTGCGACTCGCAACCT
TATTGATCGTGCGGCTGAGCTGCTCGGCAAGACGCGCACGGATTTCATGTTGGAGGCCTCTGAACGGCGAGCTGAGGAAG
TGCTGCTAGACCGCACCGTCTTCACAGTAAGCCCCGAGGTCTATACCGAATACCTTGCTCGCCTCGATGCGCCCGCCCAG
TCGAATGAGCGGTTGAAGCGCACAATGTCGACCAAAGCGCCGTGGGACGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References