Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 456527..457125 Replicon plasmid unnamed2
Accession NZ_CP025513
Organism Neorhizobium sp. SOG26

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CYG48_RS18685 Protein ID WP_118852060.1
Coordinates 456527..456820 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CYG48_RS18690 Protein ID WP_118852061.1
Coordinates 456817..457125 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYG48_RS18675 452194..454284 - 2091 WP_118852058.1 TonB-dependent siderophore receptor -
CYG48_RS18680 454857..455099 - 243 WP_199925351.1 HAD-IA family hydrolase -
CYG48_RS18685 456527..456820 - 294 WP_118852060.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CYG48_RS18690 456817..457125 - 309 WP_118852061.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CYG48_RS18695 457462..458163 - 702 WP_118852062.1 L,D-transpeptidase -
CYG48_RS18700 458276..458626 + 351 WP_118849511.1 transposase -
CYG48_RS18705 458626..459423 + 798 WP_199925137.1 IS3 family transposase -
CYG48_RS18710 459563..460297 - 735 WP_118849513.1 IS21-like element helper ATPase IstB -
CYG48_RS18715 460297..461796 - 1500 WP_118849514.1 IS21 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - adeG 1..1172176 1172176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-53)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10674.21 Da        Isoelectric Point: 5.7995

>T90465 WP_118852060.1 NZ_CP025513:c456820-456527 [Neorhizobium sp. SOG26]
VKLTWSAYALSDRDAIFTYIEADNPAAAALIDERIVAAVRRLLDFPASGRVGRIAGTRELVINGTPYIAAYATTETTVRI
LRVLHGAQEWPEYLPLS

Download         Length: 294 bp

>T90465 NZ_CP025513:c456820-456527 [Neorhizobium sp. SOG26]
GTGAAGCTTACTTGGTCTGCGTATGCGCTGTCGGACCGCGACGCCATCTTCACATACATCGAGGCAGATAATCCTGCAGC
CGCTGCTCTAATCGATGAACGGATAGTCGCCGCCGTCCGTCGCTTGCTCGACTTTCCCGCCAGTGGGCGCGTGGGTAGAA
TTGCCGGGACACGCGAACTGGTCATCAACGGAACGCCTTATATCGCCGCCTACGCCACCACCGAGACGACAGTTCGAATT
CTTCGTGTACTCCACGGCGCGCAGGAATGGCCGGAATATCTGCCGCTAAGCTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10992.37 Da        Isoelectric Point: 5.1679

>AT90465 WP_118852061.1 NZ_CP025513:c457125-456817 [Neorhizobium sp. SOG26]
MAGNALVQTRIDAEIRDRASAVLESMGLTVSDAVRIMLTRTANEGALPLELLSGSEAHDAWFRTKVLEALNDTRPDLSDE
EVEAHFAKRRSTARLKAGAAGS

Download         Length: 309 bp

>AT90465 NZ_CP025513:c457125-456817 [Neorhizobium sp. SOG26]
ATGGCCGGCAATGCACTTGTTCAAACGCGTATCGATGCCGAAATTCGAGATCGTGCTTCTGCCGTGCTCGAGAGCATGGG
CCTCACGGTATCTGACGCGGTTCGGATCATGCTGACGCGAACTGCAAACGAGGGGGCGCTGCCTCTTGAGCTTCTTTCTG
GCAGCGAAGCGCATGACGCCTGGTTTCGGACCAAGGTGCTCGAAGCGTTGAACGATACTCGGCCGGATTTATCGGACGAA
GAGGTCGAGGCGCATTTTGCCAAACGCCGATCAACCGCCCGCCTTAAAGCTGGTGCGGCAGGATCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References