Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 362797..363587 Replicon plasmid unnamed2
Accession NZ_CP025513
Organism Neorhizobium sp. SOG26

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CYG48_RS18255 Protein ID WP_118851994.1
Coordinates 362797..363294 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag CYG48_RS18260 Protein ID WP_118851995.1
Coordinates 363291..363587 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYG48_RS18230 359070..359696 - 627 WP_118851990.1 CGNR zinc finger domain-containing protein -
CYG48_RS18235 359783..360745 + 963 WP_118851991.1 EamA family transporter -
CYG48_RS18240 360884..361216 - 333 WP_118851992.1 antibiotic biosynthesis monooxygenase -
CYG48_RS18245 361216..362046 - 831 WP_118852840.1 helix-turn-helix transcriptional regulator -
CYG48_RS18250 362145..362507 - 363 WP_118851993.1 nuclear transport factor 2 family protein -
CYG48_RS18255 362797..363294 - 498 WP_118851994.1 GNAT family N-acetyltransferase Toxin
CYG48_RS18260 363291..363587 - 297 WP_118851995.1 DUF1778 domain-containing protein Antitoxin
CYG48_RS18265 363889..364482 + 594 WP_118851996.1 cupin domain-containing protein -
CYG48_RS18270 364554..365861 + 1308 WP_118851997.1 4-aminobutyrate--2-oxoglutarate transaminase -
CYG48_RS18275 365892..367445 + 1554 WP_118851998.1 acetolactate synthase large subunit -
CYG48_RS18280 367446..367826 - 381 WP_118851999.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - adeG 1..1172176 1172176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(34-142)

Antitoxin

Vibrio phage ICP1, Orf50

(16-90)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17785.40 Da        Isoelectric Point: 8.0185

>T90464 WP_118851994.1 NZ_CP025513:c363294-362797 [Neorhizobium sp. SOG26]
VILTAPAPLADYHELEEFDSGVQQLDDWLRRRARANQAGGASRTFVACEGNRVVAYYALASGAVKPAEAPGRFRRNMPDP
LPVAVLGRLAIDRSYQSRGLGRALVRDAGLRLLNAAEILGIRGVLVHAISDDARAFYEAVGFLPSPSDPMMLMIGLKDLS
NALNA

Download         Length: 498 bp

>T90464 NZ_CP025513:c363294-362797 [Neorhizobium sp. SOG26]
GTGATACTAACTGCGCCTGCTCCCTTAGCCGATTATCATGAACTGGAAGAGTTTGATTCCGGCGTTCAACAACTGGACGA
CTGGTTGCGTCGACGAGCCCGTGCCAATCAGGCAGGTGGGGCATCTCGTACGTTTGTGGCCTGCGAGGGAAATCGCGTTG
TTGCCTACTACGCGCTCGCCTCCGGCGCAGTGAAGCCGGCAGAAGCACCAGGCCGTTTCAGGCGAAACATGCCGGACCCG
CTCCCAGTCGCAGTACTTGGTCGATTGGCTATTGATCGATCTTACCAGAGTCGAGGTCTAGGTCGGGCGTTGGTCCGTGA
TGCAGGCCTGCGCCTGCTTAATGCCGCCGAAATACTTGGTATCCGAGGCGTACTGGTGCATGCCATTTCGGATGATGCGC
GTGCCTTCTATGAAGCTGTCGGATTTCTGCCTTCTCCGTCCGATCCGATGATGCTGATGATCGGATTGAAAGACCTCAGC
AACGCATTGAACGCGTAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11114.63 Da        Isoelectric Point: 9.7295

>AT90464 WP_118851995.1 NZ_CP025513:c363587-363291 [Neorhizobium sp. SOG26]
MPTSHTSKNVNASVPLNIRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTVFTVSPEVYNQYLARLDAPAQ
SNERLKRTMSTKAPWDEA

Download         Length: 297 bp

>AT90464 NZ_CP025513:c363587-363291 [Neorhizobium sp. SOG26]
ATGCCGACGTCACACACCAGCAAGAATGTGAACGCAAGCGTTCCGTTGAATATCCGTATCAAGCCCGCGACTCGCAACCT
TATTGATCGTGCGGCTGAGTTGCTAGGCAAGACGCGCACGGATTTCATGTTGGAGGCCTCTGAACGGCGAGCTGAGGAAG
TGCTGCTAGACCGCACCGTCTTCACAGTAAGCCCCGAGGTCTATAACCAATACCTTGCTCGCCTCGATGCGCCCGCCCAG
TCGAATGAGCGGTTGAAGCGCACAATGTCGACCAAAGCGCCGTGGGACGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References