Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1984375..1984891 Replicon chromosome
Accession NZ_CP025512
Organism Neorhizobium sp. SOG26

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CYG48_RS09830 Protein ID WP_118850219.1
Coordinates 1984375..1984656 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CYG48_RS09835 Protein ID WP_118851588.1
Coordinates 1984646..1984891 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYG48_RS09805 1979871..1980098 - 228 WP_118850215.1 hypothetical protein -
CYG48_RS09810 1980216..1981124 + 909 WP_118851587.1 LysR family transcriptional regulator -
CYG48_RS09815 1981132..1981488 - 357 WP_118850216.1 hypothetical protein -
CYG48_RS09820 1981805..1983031 + 1227 WP_118850217.1 urate hydroxylase PuuD -
CYG48_RS09825 1983028..1984338 + 1311 WP_118850218.1 guanine deaminase -
CYG48_RS09830 1984375..1984656 - 282 WP_118850219.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CYG48_RS09835 1984646..1984891 - 246 WP_118851588.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CYG48_RS09840 1985094..1986239 + 1146 WP_118850220.1 alpha-hydroxy-acid oxidizing protein -
CYG48_RS09845 1986423..1986992 + 570 WP_118850221.1 type 1 glutamine amidotransferase -
CYG48_RS09850 1987142..1987399 + 258 Protein_1947 NAD(P)-dependent oxidoreductase -
CYG48_RS09855 1987487..1987969 - 483 WP_118850222.1 pyridoxamine 5'-phosphate oxidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-74)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10931.77 Da        Isoelectric Point: 10.9315

>T90462 WP_118850219.1 NZ_CP025512:c1984656-1984375 [Neorhizobium sp. SOG26]
MSYKLEFLPSARKEWDRLGATLKHQFKKKLGERLKQPQVSADALRGMPNHYKIKLRAAGYRLVYRVEDERITVVVVAVGK
RERSEVYDTARKR

Download         Length: 282 bp

>T90462 NZ_CP025512:c1984656-1984375 [Neorhizobium sp. SOG26]
ATGAGCTATAAGCTCGAGTTCCTGCCGTCCGCCCGCAAGGAGTGGGACCGCCTCGGCGCAACGCTGAAGCATCAGTTCAA
GAAGAAACTCGGCGAAAGGCTGAAGCAACCGCAGGTGTCGGCCGATGCGCTGCGAGGCATGCCGAACCACTACAAGATCA
AGCTGCGCGCCGCCGGCTACCGGCTCGTCTACCGGGTGGAAGACGAGCGGATCACGGTTGTCGTCGTGGCGGTCGGCAAG
CGGGAGCGCTCGGAAGTTTACGACACGGCCAGGAAGCGATAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8648.92 Da        Isoelectric Point: 4.2404

>AT90462 WP_118851588.1 NZ_CP025512:c1984891-1984646 [Neorhizobium sp. SOG26]
MQRVEAPIAVSVSELKKNPSALVEGATGSPIAILNHNRVMAYMVPATTYEAMVDALDDQALVELAKARADEKGVPVDLDE
L

Download         Length: 246 bp

>AT90462 NZ_CP025512:c1984891-1984646 [Neorhizobium sp. SOG26]
ATGCAGCGCGTGGAAGCCCCGATAGCCGTCAGTGTCTCCGAACTGAAGAAGAACCCCTCGGCGTTGGTGGAAGGGGCGAC
CGGCTCTCCCATCGCGATCCTGAACCACAACCGCGTCATGGCCTACATGGTGCCGGCTACGACCTATGAGGCCATGGTGG
ACGCTCTTGACGACCAGGCGCTGGTCGAACTCGCCAAGGCGCGTGCCGATGAGAAGGGCGTGCCGGTCGACCTTGATGAG
CTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References