90460

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 608107..608587 Replicon chromosome
Accession NZ_CP025512
Organism Neorhizobium sp. SOG26

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag CYG48_RS02990 Protein ID WP_118849019.1
Coordinates 608315..608587 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag CYG48_RS02985 Protein ID WP_118849018.1
Coordinates 608107..608331 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYG48_RS02965 603597..603917 + 321 WP_118849015.1 HigA family addiction module antidote protein -
CYG48_RS02970 603921..606155 - 2235 WP_118849016.1 penicillin-binding protein -
CYG48_RS02975 606376..606849 + 474 WP_118851463.1 YcgN family cysteine cluster protein -
CYG48_RS02980 606963..608066 + 1104 WP_118849017.1 hypothetical protein -
CYG48_RS02985 608107..608331 + 225 WP_118849018.1 ribbon-helix-helix protein, CopG family Antitoxin
CYG48_RS02990 608315..608587 + 273 WP_118849019.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CYG48_RS02995 608659..611103 + 2445 WP_118849020.1 heavy metal translocating P-type ATPase -
CYG48_RS03000 611100..611534 + 435 WP_118849021.1 Cu(I)-responsive transcriptional regulator -
CYG48_RS03005 611578..611778 + 201 WP_118849022.1 heavy-metal-associated domain-containing protein -
CYG48_RS03010 612014..612646 - 633 WP_118849023.1 porin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-47)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10588.20 Da        Isoelectric Point: 10.6000

>T90460 WP_118849019.1 NZ_CP025512:608315-608587 [Neorhizobium sp. SOG26]
MAWTIELQRDAQRDLAKLGHDNARRILKFLHGRVAGLEDPRSIGEALKGPSLEDFWKYRVGDYRIIAHIRDDVVQVLVVR
IGHRREVYRR

Download         Length: 273 bp

>T90460 NZ_CP025512:608315-608587 [Neorhizobium sp. SOG26]
ATGGCCTGGACGATTGAGCTGCAGCGTGATGCACAGCGCGATCTGGCTAAACTCGGCCATGACAATGCCCGACGGATCCT
GAAGTTTCTTCATGGGCGGGTCGCGGGACTTGAGGACCCGCGATCGATTGGCGAGGCGCTGAAAGGTCCGAGCCTGGAGG
ACTTCTGGAAATACCGGGTAGGCGACTACAGGATCATCGCGCATATTCGCGATGATGTCGTGCAGGTTCTCGTCGTGCGT
ATCGGGCACCGCCGCGAAGTCTATCGGCGATAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8520.64 Da        Isoelectric Point: 4.4550

>AT90460 WP_118849018.1 NZ_CP025512:608107-608331 [Neorhizobium sp. SOG26]
MLALRLPPDIEARLDELARLTGRSKSYYAREAILTHLDDLEDIYLAQERLESLRRGESDSVPLSQVMKQYGLDD

Download         Length: 225 bp

>AT90460 NZ_CP025512:608107-608331 [Neorhizobium sp. SOG26]
ATGCTCGCCCTTCGATTGCCGCCCGACATAGAAGCCCGCCTTGATGAGCTTGCCCGGCTGACCGGCCGCAGCAAGAGCTA
CTATGCGCGGGAAGCGATCCTCACCCATCTTGATGATCTGGAAGACATTTACCTTGCCCAGGAGCGGCTCGAAAGCCTGC
GCCGTGGTGAGAGCGACAGCGTGCCATTGTCCCAGGTCATGAAACAGTATGGCCTGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References