Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 2087557..2089277 Replicon chromosome
Accession NZ_CP025491
Organism Legionella sainthelensi strain LA01-117

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag CAB17_RS09275 Protein ID WP_101900897.1
Coordinates 2087557..2088489 (-) Length 311 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag CAB17_RS09280 Protein ID WP_101900898.1
Coordinates 2088486..2089277 (-) Length 264 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAB17_RS09250 2083932..2084552 + 621 WP_101900893.1 hypothetical protein -
CAB17_RS09255 2084591..2084827 + 237 WP_101900894.1 hypothetical protein -
CAB17_RS09260 2084891..2085367 + 477 WP_101900895.1 hypothetical protein -
CAB17_RS09265 2085381..2085884 + 504 WP_101900896.1 hypothetical protein -
CAB17_RS09270 2085875..2087438 + 1564 Protein_1812 DUF2779 domain-containing protein -
CAB17_RS09275 2087557..2088489 - 933 WP_101900897.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CAB17_RS09280 2088486..2089277 - 792 WP_101900898.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
CAB17_RS09285 2089417..2089692 + 276 WP_101900899.1 hypothetical protein -
CAB17_RS09290 2089748..2090239 + 492 WP_129556865.1 hypothetical protein -
CAB17_RS09295 2091183..2092658 - 1476 WP_101900901.1 hypothetical protein -
CAB17_RS09300 2093308..2094231 + 924 WP_101900902.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-264)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(96-254)


Sequences

Toxin        


Download         Length: 311 a.a.        Molecular weight: 35423.39 Da        Isoelectric Point: 7.2175

>T90426 WP_101900897.1 NZ_CP025491:c2088489-2087557 [Legionella sainthelensi]
MNKQSPYYKQVLLLIRLIPIVEKETCFALKGGTAINLFVRDFPRLSVDIDLAYLPLEPREIALANVRNALAGIAANINKM
PDLTAVLQDNKPDEMRIIVEDKSFLNRGTQIKIEVSPVARGTLLPPIELDVVAAVENEFGFASMKVVSLPDLYGGKLCAA
LDRQHPRDLFDIKVLLENQKIDRELFNGFITYLLSHKRPISEIMNPRWKDITQVFEKEFKGMTAEPVALEALRSIPEKMI
QGLKENFNQQDYDFLVSFKKGEPDWSLACSDQIQYLPAVQWKLLNISKMPKQKHIDSVNLLQKTMEQWLK

Download         Length: 933 bp

>T90426 NZ_CP025491:c2088489-2087557 [Legionella sainthelensi]
ATGAATAAACAGTCACCTTATTACAAGCAAGTTTTATTACTTATTCGTTTAATTCCTATCGTTGAAAAGGAAACTTGTTT
TGCTTTAAAAGGTGGCACTGCCATTAATTTATTTGTGCGAGATTTTCCTCGGTTATCTGTGGATATTGATCTTGCGTATT
TACCCCTTGAACCTCGTGAGATAGCTTTAGCCAACGTGCGTAATGCATTAGCTGGTATTGCGGCAAATATTAATAAAATG
CCAGATCTAACCGCTGTTTTACAAGATAACAAACCAGATGAAATGCGAATTATTGTTGAGGATAAGTCTTTTCTAAATAG
AGGGACTCAAATCAAGATAGAGGTTTCACCTGTAGCGCGTGGAACTCTTTTGCCTCCTATTGAGCTTGATGTTGTTGCTG
CGGTGGAAAATGAGTTTGGTTTTGCATCAATGAAAGTAGTTTCTTTACCTGATCTTTATGGTGGTAAATTATGCGCAGCT
TTAGATCGCCAACATCCAAGGGATCTTTTTGATATTAAGGTGTTATTAGAAAATCAAAAAATAGATCGAGAGCTTTTTAA
TGGATTTATTACTTATCTTTTGAGTCATAAAAGGCCTATTTCAGAAATTATGAACCCACGATGGAAGGATATAACTCAAG
TTTTTGAAAAGGAATTTAAAGGAATGACTGCTGAACCAGTTGCCCTTGAAGCACTTAGATCAATACCAGAAAAAATGATT
CAGGGTCTTAAAGAGAATTTTAATCAGCAGGATTATGATTTTTTAGTCTCGTTTAAAAAGGGTGAGCCTGATTGGTCTCT
TGCATGTAGCGATCAGATTCAATATTTACCGGCAGTACAATGGAAGCTTTTAAATATTAGTAAGATGCCTAAACAAAAAC
ACATTGATTCTGTTAACTTACTACAAAAAACGATGGAACAATGGCTTAAGTAG

Antitoxin


Download         Length: 264 a.a.        Molecular weight: 29896.42 Da        Isoelectric Point: 9.9545

>AT90426 WP_101900898.1 NZ_CP025491:c2089277-2088486 [Legionella sainthelensi]
MSSKINWLLNNIASGEILLQSWLSSHGITPQLARKYCQSQWLVKLGVGVYYRAGRKPEWQNAVYCLQNQSRSMIHLAGLT
SLTQQGKAHYLQLTAQSIWINVQAKTILPKWFKTFPELAIFSNPAPRWEIIKTSKLNTLDDSDLITIEVDGVNLKASNQE
LAAFEVLEAVPSTLSFEHAAELFQGLVNLSPRRIEAILKRSGSIQTNRLFLFFGHFYKHPWVKRLNESSINLGAGKRQIV
QDGKLEKQYQITVPEQFISSEQI

Download         Length: 792 bp

>AT90426 NZ_CP025491:c2089277-2088486 [Legionella sainthelensi]
ATGTCATCAAAAATAAACTGGCTGTTGAATAATATTGCTTCTGGTGAAATCTTGCTCCAGTCTTGGTTATCAAGTCATGG
GATTACCCCGCAATTAGCAAGAAAGTACTGTCAAAGCCAATGGTTAGTGAAATTGGGAGTAGGTGTTTATTATCGTGCAG
GGCGTAAACCTGAATGGCAAAATGCAGTTTATTGCCTTCAGAATCAGAGCAGGTCCATGATTCATCTTGCTGGTTTAACC
AGTTTGACTCAACAGGGTAAAGCTCATTATCTACAGTTGACAGCACAATCTATTTGGATAAATGTTCAAGCAAAAACGAT
TTTACCAAAGTGGTTTAAAACTTTTCCAGAATTAGCCATTTTTAGCAATCCGGCACCACGCTGGGAAATCATTAAAACAT
CCAAGTTAAATACTCTCGATGACAGTGACTTAATTACTATAGAAGTAGATGGAGTTAATTTAAAGGCAAGTAATCAGGAG
CTAGCGGCCTTTGAGGTGCTGGAGGCTGTACCTTCCACTTTGTCATTTGAACACGCAGCAGAACTTTTTCAGGGGTTGGT
AAACTTAAGCCCACGGAGAATAGAGGCTATTTTAAAAAGAAGCGGATCTATTCAAACTAACCGCCTATTTTTATTTTTTG
GCCATTTCTACAAGCATCCATGGGTCAAACGGTTGAATGAGTCGTCGATTAATCTAGGTGCAGGTAAACGTCAAATAGTT
CAAGACGGTAAATTAGAAAAGCAATATCAAATCACCGTTCCAGAACAATTCATAAGTAGTGAGCAAATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References