Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3425351..3425496 Replicon chromosome
Accession NZ_CP025461
Organism Klebsiella pneumoniae strain F44

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3425358..3425460 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3425351..3425496 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CYE02_RS17480 3420883..3422316 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CYE02_RS17485 3422432..3422671 + 240 WP_002911393.1 YebV family protein -
CYE02_RS17490 3422769..3422960 + 192 WP_002911395.1 YebW family protein -
CYE02_RS17495 3422957..3423610 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
CYE02_RS17500 3423767..3424735 + 969 WP_004151446.1 VirK/YbjX family protein -
CYE02_RS30880 3424840..3424983 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3425351..3425496 + 146 - - Antitoxin
- 3425358..3425460 - 103 - - Toxin
CYE02_RS17510 3425619..3425957 - 339 WP_002911404.1 YebY family protein -
CYE02_RS17515 3425974..3426843 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CYE02_RS17520 3426847..3427221 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CYE02_RS17525 3427334..3427564 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CYE02_RS17530 3427643..3428302 + 660 WP_002911407.1 exodeoxyribonuclease X -
CYE02_RS17535 3428306..3430366 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T90370 NZ_CP025461:c3425460-3425358 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT90370 NZ_CP025461:3425351-3425496 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References