Detailed information of TA system TA090331

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-CC2985
• Location: 127386..127926
• Replicon: plasmid pPZ03
• Accession: NZ_CP025433
• Organism: Paracoccus zhejiangensis strain J6

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: CX676_RS22200
• Protein ID: WP_101754948.1
• Coordinates: 127618..127926 (+)
• Length: 103 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: CX676_RS22195
• Protein ID: WP_101754972.1
• Coordinates: 127386..127631 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CX676_RS22180	123044..124258	-	1215	WP_101754946.1	replication initiation protein	-
CX676_RS22185	124776..126194	+	1419	WP_101754971.1	AAA family ATPase	-
CX676_RS22190	126172..127281	+	1110	WP_101754947.1	ParB N-terminal domain-containing protein	-
CX676_RS22195	127386..127631	+	246	WP_101754972.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
CX676_RS22200	127618..127926	+	309	WP_101754948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CX676_RS22205	127931..128998	-	1068	WP_101754949.1	tyrosine-type recombinase/integrase	-
CX676_RS22210	129126..130017	+	892	Protein_129	DUF1403 family protein	-
CX676_RS22215	130020..130625	+	606	WP_101754950.1	SMC-Scp complex subunit ScpB	-
CX676_RS22220	130697..131677	-	981	Protein_131	IS110 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..150390	150390

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (9-94)

Antitoxin

• Antitoxin ParD (2-80)

Sequences

Toxin

Protein

• Length: 103 a.a.
• Molecular weight: 11586.93 Da
• Isoelectric Point: 4.8330

>T90331 WP_101754948.1 NZ_CP025433:127618-127926 [Paracoccus zhejiangensis]
MPESNGWTLRPSAESDLSEIWRQGAATWGVEQAERYTDGLFAVFDLLAAFPDLGRERREFSPPVRIHPNGSHLVIYRQDG
QGVEIIRILHGHQNLTAYLLED

Nucleotide

• Length: 309 bp

>T90331 NZ_CP025433:127618-127926 [Paracoccus zhejiangensis]
ATGCCGGAAAGTAACGGCTGGACCCTTCGGCCCTCCGCTGAATCCGACCTGTCAGAAATCTGGCGCCAGGGGGCCGCGAC
CTGGGGTGTCGAACAGGCAGAGCGCTATACGGACGGCTTGTTCGCGGTCTTCGACCTTCTGGCCGCCTTTCCGGACTTGG
GACGGGAGCGCAGGGAGTTTTCCCCGCCCGTCAGGATCCATCCCAATGGCTCGCATCTCGTGATCTATCGGCAAGACGGG
CAGGGGGTCGAGATCATCCGCATCCTGCATGGACACCAGAACCTGACGGCCTATCTGCTGGAGGACTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9059.25 Da
• Isoelectric Point: 10.5420

>AT90331 WP_101754972.1 NZ_CP025433:127386-127631 [Paracoccus zhejiangensis]
MGTMNISLPDPMKSWVEDQAKSGRYANSSDYVRDLIRRDRQRQQAITEIQAAIETGIASGPAKPLDRAAFRARMRAEHAG
K

Nucleotide

• Length: 246 bp

>AT90331 NZ_CP025433:127386-127631 [Paracoccus zhejiangensis]
ATGGGCACGATGAACATCTCGCTACCGGACCCTATGAAGTCCTGGGTTGAAGATCAGGCGAAATCAGGTCGTTACGCGAA
TTCCAGCGACTATGTGCGTGATCTGATCCGCCGCGACCGGCAGCGCCAGCAGGCGATCACCGAGATCCAGGCCGCGATCG
AGACCGGGATCGCCAGCGGACCCGCCAAGCCGCTTGATCGCGCGGCCTTCAGGGCTCGGATGCGCGCGGAACATGCCGGA
AAGTAA