Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RHH
Location 22347..22915 Replicon plasmid pPZ02
Accession NZ_CP025432
Organism Paracoccus zhejiangensis strain J6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CX676_RS20605 Protein ID WP_101754684.1
Coordinates 22347..22655 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CX676_RS20610 Protein ID WP_101754685.1
Coordinates 22652..22915 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CX676_RS22655 18566..18703 - 138 WP_007803572.1 hypothetical protein -
CX676_RS20580 18700..19086 - 387 WP_101754682.1 mercury resistance system transport protein MerF -
CX676_RS22660 19083..19334 - 252 WP_072629817.1 hypothetical protein -
CX676_RS20585 19365..19667 - 303 WP_040545980.1 hypothetical protein -
CX676_RS20590 19683..20090 - 408 WP_007803565.1 mercury transporter -
CX676_RS20595 20167..20580 + 414 WP_153218054.1 helix-turn-helix domain-containing protein -
CX676_RS20600 20785..22125 - 1341 WP_101754683.1 hypothetical protein -
CX676_RS20605 22347..22655 - 309 WP_101754684.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CX676_RS20610 22652..22915 - 264 WP_101754685.1 ribbon-helix-helix domain-containing protein Antitoxin
CX676_RS20615 23068..23340 + 273 WP_157936024.1 hypothetical protein -
CX676_RS20620 23345..23965 + 621 WP_101754687.1 SOS response-associated peptidase -
CX676_RS20625 24614..25828 - 1215 WP_198590384.1 acyl-CoA dehydrogenase -
CX676_RS20630 25899..27554 - 1656 WP_101754688.1 electron transfer flavoprotein-ubiquinone oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..214101 214101


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11144.79 Da        Isoelectric Point: 7.0119

>T90328 WP_101754684.1 NZ_CP025432:c22655-22347 [Paracoccus zhejiangensis]
MKTLLIAEPAGRDLEAIVDYIARENPAAAENVYRQIARTAAKLPEFPALGRPGRFSGTREMNVAGSPYLIVYEVNVEAVT
ILAVFHTSRNLAAALRDRMEGS

Download         Length: 309 bp

>T90328 NZ_CP025432:c22655-22347 [Paracoccus zhejiangensis]
TTGAAGACACTTCTCATTGCCGAGCCGGCCGGGCGAGACCTTGAAGCCATCGTGGATTATATCGCGCGGGAAAACCCGGC
TGCGGCCGAGAATGTGTACAGGCAGATTGCCCGAACAGCCGCGAAGCTTCCGGAGTTTCCCGCACTCGGCCGTCCGGGGC
GCTTTTCCGGGACGCGGGAAATGAATGTGGCAGGGTCACCCTATCTCATTGTCTACGAGGTCAACGTCGAGGCAGTCACA
ATTCTGGCCGTCTTTCACACCTCCCGCAATCTCGCAGCGGCCCTTCGCGATCGTATGGAAGGCAGCTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9504.61 Da        Isoelectric Point: 4.7318

>AT90328 WP_101754685.1 NZ_CP025432:c22915-22652 [Paracoccus zhejiangensis]
MEHTMPQRAETEPMTVRTARVSEIDALAAAMDRSRNYVVNQAIDQFLEANAWQMERIAAGVAAAREGNVSSADDVFGAIA
TKHGWQA

Download         Length: 264 bp

>AT90328 NZ_CP025432:c22915-22652 [Paracoccus zhejiangensis]
TTGGAGCACACCATGCCGCAGCGCGCCGAAACAGAACCCATGACCGTCCGCACAGCCAGGGTCTCGGAGATCGATGCCTT
GGCCGCCGCGATGGATCGTTCTCGCAACTATGTGGTCAATCAGGCGATCGATCAGTTTCTCGAAGCCAACGCTTGGCAAA
TGGAACGGATCGCGGCCGGGGTGGCCGCAGCGCGCGAGGGTAACGTCAGTTCTGCCGACGACGTCTTTGGCGCCATTGCC
ACCAAGCATGGCTGGCAGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References