Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 193308..193830 Replicon plasmid p220k
Accession NZ_CP025340
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain BL10

Toxin (Protein)


Gene name relE Uniprot ID D0QMR1
Locus tag CTI29_RS26730 Protein ID WP_000220561.1
Coordinates 193549..193830 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3CAG1
Locus tag CTI29_RS26725 Protein ID WP_000121743.1
Coordinates 193308..193559 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTI29_RS26690 188755..189564 - 810 WP_000031377.1 DsbA family protein -
CTI29_RS26695 189671..190282 + 612 WP_000620990.1 hypothetical protein -
CTI29_RS26700 190342..190764 - 423 WP_000025803.1 hypothetical protein -
CTI29_RS26705 190798..191190 - 393 WP_000843244.1 hypothetical protein -
CTI29_RS26710 191215..191556 - 342 Protein_194 thioredoxin fold domain-containing protein -
CTI29_RS26715 191572..192269 - 698 Protein_195 IS1-like element IS1A family transposase -
CTI29_RS26725 193308..193559 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin
CTI29_RS26730 193549..193830 + 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CTI29_RS27010 194069..194161 - 93 Protein_198 IS6 family transposase -
CTI29_RS26740 194327..195526 - 1200 WP_000948429.1 IS91 family transposase -
CTI29_RS26745 195536..195724 - 189 WP_000957857.1 hypothetical protein -
CTI29_RS26750 195844..197274 + 1431 Protein_201 IS4-like element IS50R family transposase -
CTI29_RS26755 197303..198097 + 795 WP_000572405.1 aminoglycoside O-phosphotransferase APH(3')-IIa -
CTI29_RS26760 198118..198354 + 237 Protein_203 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..220023 220023


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T90150 WP_000220561.1 NZ_CP025340:193549-193830 [Salmonella enterica subsp. enterica serovar Typhimurium]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T90150 NZ_CP025340:193549-193830 [Salmonella enterica subsp. enterica serovar Typhimurium]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 10784.64 Da        Isoelectric Point: 12.7191

>AT90150 WP_000121743.1 NZ_CP025340:193308-193559 [Salmonella enterica subsp. enterica serovar Typhimurium]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Download         Length: 252 bp

>AT90150 NZ_CP025340:193308-193559 [Salmonella enterica subsp. enterica serovar Typhimurium]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S5I302

Antitoxin

Source ID Structure
AlphaFold DB A0A3S5I301

References