Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6060186..6060775 Replicon chromosome
Accession NZ_CP025309
Organism Pseudomonas chlororaphis strain Lzh-T5

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CXP47_RS27100 Protein ID WP_028683468.1
Coordinates 6060476..6060775 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag CXP47_RS27095 Protein ID WP_007924096.1
Coordinates 6060186..6060479 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXP47_RS27075 6055727..6056890 - 1164 WP_101283689.1 acyltransferase -
CXP47_RS27080 6057085..6058275 - 1191 WP_028683472.1 serine hydrolase -
CXP47_RS27085 6058402..6059289 + 888 WP_009051074.1 LysR family transcriptional regulator -
CXP47_RS27090 6059661..6060053 + 393 WP_028683470.1 hypothetical protein -
CXP47_RS27095 6060186..6060479 - 294 WP_007924096.1 putative addiction module antidote protein Antitoxin
CXP47_RS27100 6060476..6060775 - 300 WP_028683468.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CXP47_RS27105 6060946..6061395 + 450 WP_009051078.1 DUF3828 domain-containing protein -
CXP47_RS27110 6061420..6062430 - 1011 WP_188056704.1 NAD(P)-dependent alcohol dehydrogenase -
CXP47_RS27115 6062488..6062787 - 300 WP_009051080.1 ArsR family transcriptional regulator -
CXP47_RS27120 6062851..6063942 - 1092 WP_009051081.1 nitrite reductase, copper-containing -
CXP47_RS27125 6064203..6064445 - 243 WP_009051082.1 hypothetical protein -
CXP47_RS27130 6064931..6065173 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11256.97 Da        Isoelectric Point: 10.4277

>T90048 WP_028683468.1 NZ_CP025309:c6060775-6060476 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

>T90048 NZ_CP025309:c6060775-6060476 [Pseudomonas chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAACGGCCTTGCCGGGGACGTGTCCCCGGTGGGCGAAGGCGTCAGCGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGAGTTTATTTCCAGCAGCTTGGTTCGCAACTTGTCATTTTGTTATGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10430.94 Da        Isoelectric Point: 5.6558

>AT90048 WP_007924096.1 NZ_CP025309:c6060479-6060186 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp

>AT90048 NZ_CP025309:c6060479-6060186 [Pseudomonas chlororaphis]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAGGCCATCGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGATATGACTGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References