Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1505054..1505582 Replicon chromosome
Accession NZ_CP025309
Organism Pseudomonas chlororaphis strain Lzh-T5

Toxin (Protein)


Gene name relE Uniprot ID A0A7S5LMJ4
Locus tag CXP47_RS06845 Protein ID WP_038581545.1
Coordinates 1505054..1505353 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7S5HLJ1
Locus tag CXP47_RS06850 Protein ID WP_038581543.1
Coordinates 1505343..1505582 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXP47_RS06825 1500961..1501743 - 783 WP_101281929.1 aldolase -
CXP47_RS06830 1501903..1502445 + 543 WP_007922237.1 XRE family transcriptional regulator -
CXP47_RS06835 1502655..1503674 - 1020 WP_009047445.1 DUF4917 family protein -
CXP47_RS06840 1503832..1504980 + 1149 WP_038630803.1 L-threonine dehydrogenase -
CXP47_RS06845 1505054..1505353 - 300 WP_038581545.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CXP47_RS06850 1505343..1505582 - 240 WP_038581543.1 ribbon-helix-helix protein, CopG family Antitoxin
CXP47_RS06855 1505719..1506135 + 417 WP_101281930.1 fosfomycin resistance glutathione transferase -
CXP47_RS06860 1506263..1506901 + 639 WP_016702101.1 LysE family translocator -
CXP47_RS06865 1507013..1508353 + 1341 WP_101281931.1 sensor domain-containing diguanylate cyclase -
CXP47_RS06870 1508493..1509017 + 525 WP_009047451.1 DUF4142 domain-containing protein -
CXP47_RS06875 1509111..1510001 - 891 WP_101284080.1 phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-82)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11487.13 Da        Isoelectric Point: 10.8916

>T90044 WP_038581545.1 NZ_CP025309:c1505353-1505054 [Pseudomonas chlororaphis]
MHVEWLRSALKNLDDEAAYIAQDSPQAAAEFVKAILSSIQHLSRFPASGREGRLPGTREWVVPNRPYLIPYRVRQGRLQI
LRIFHTRRLPPAGWQDDRQ

Download         Length: 300 bp

>T90044 NZ_CP025309:c1505353-1505054 [Pseudomonas chlororaphis]
ATGCACGTTGAGTGGCTGCGCAGCGCCCTCAAGAACCTCGATGACGAAGCCGCCTACATTGCACAGGACAGTCCTCAGGC
CGCCGCGGAATTCGTCAAAGCCATCCTGAGTAGCATTCAACACCTGAGCCGTTTTCCTGCCAGTGGTCGCGAAGGTCGCC
TGCCCGGTACCCGGGAGTGGGTGGTCCCCAATCGTCCTTACCTGATCCCCTACCGCGTACGTCAGGGACGCCTGCAGATA
CTGCGGATTTTCCACACCCGGCGCTTGCCGCCTGCCGGTTGGCAAGACGACCGCCAATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8648.73 Da        Isoelectric Point: 4.5535

>AT90044 WP_038581543.1 NZ_CP025309:c1505582-1505343 [Pseudomonas chlororaphis]
MSVMSLRLPDDVADTLAHLAKATGRSKSFLAVDALREYLAREAWQINEIQKALTEAEAGDFASAEELDGVLNKWTGNAR

Download         Length: 240 bp

>AT90044 NZ_CP025309:c1505582-1505343 [Pseudomonas chlororaphis]
ATGTCCGTCATGTCCTTGCGCCTGCCCGATGATGTTGCCGATACCCTGGCTCACTTGGCCAAGGCGACAGGCCGCAGCAA
GTCATTCCTCGCTGTGGATGCACTGAGAGAATATCTGGCCCGCGAAGCCTGGCAAATCAACGAGATCCAGAAAGCCCTGA
CTGAAGCAGAGGCAGGCGACTTCGCCAGCGCCGAAGAGCTGGATGGCGTACTCAACAAATGGACTGGCAATGCACGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7S5LMJ4

Antitoxin

Source ID Structure
AlphaFold DB A0A7S5HLJ1

References