Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 202742..203258 Replicon chromosome
Accession NZ_CP025309
Organism Pseudomonas chlororaphis strain Lzh-T5

Toxin (Protein)


Gene name stbE Uniprot ID A0A285EY61
Locus tag CXP47_RS00860 Protein ID WP_009041601.1
Coordinates 202977..203258 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554PKE4
Locus tag CXP47_RS00855 Protein ID WP_009046356.1
Coordinates 202742..202987 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXP47_RS00830 198510..199505 + 996 WP_101281621.1 sulfotransferase family protein -
CXP47_RS00835 199471..200229 - 759 WP_009046352.1 slipin family protein -
CXP47_RS00840 200231..201616 - 1386 WP_009046353.1 nodulation protein NfeD -
CXP47_RS00845 201840..202301 + 462 WP_016705004.1 YbaK/EbsC family protein -
CXP47_RS00850 202432..202677 + 246 WP_009046355.1 DUF2789 domain-containing protein -
CXP47_RS00855 202742..202987 + 246 WP_009046356.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CXP47_RS00860 202977..203258 + 282 WP_009041601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CXP47_RS00865 203391..203819 + 429 WP_028681511.1 winged helix DNA-binding protein -
CXP47_RS00870 203816..205900 + 2085 WP_101281622.1 FUSC family protein -
CXP47_RS00875 205897..206106 + 210 WP_007932080.1 DUF1656 domain-containing protein -
CXP47_RS00880 206103..206999 + 897 WP_101281623.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10879.81 Da        Isoelectric Point: 10.5797

>T90042 WP_009041601.1 NZ_CP025309:202977-203258 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

>T90042 NZ_CP025309:202977-203258 [Pseudomonas chlororaphis]
ATGACTTATAAGCTCCAGTTTCTGCCTTCGGCGCGCAAGGAATGGGACAAGCTCGGTCATACCCTGCGCGAGCAATTCAA
GAAGAAGCTGGCCGAGCGCCTGGAAATGCCGCGGGTGCCCGCGGACGCCCTTCACGGTATGGCGGACTGCTACAAGATCA
AGCTCAAGGCCTCTGGCTATCGCCTGGTTTACCAAGTGATCGAGGATCAGGTCGTGGTTTCGGTGGTGGCCGTGGGCAAA
CGTGAACGCAGTGCCGTGTATGAGCGGGCCCGAAAGCGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8814.14 Da        Isoelectric Point: 4.7164

>AT90042 WP_009046356.1 NZ_CP025309:202742-202987 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLNGAQGGAVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp

>AT90042 NZ_CP025309:202742-202987 [Pseudomonas chlororaphis]
ATGCAAAGCGTATTGGCTGATAAAGCTGTCAGCGTGTCTGAACTGAAAAAAAATCCTTCGGCTGTCCTGAACGGCGCACA
GGGTGGTGCGGTTGCGGTGCTCAATCACAACCGGGTCATGGGCTATATGGTCCCGGCCGACGTGTTTGAAGCCATGATGG
AGCGTCTTGACGATCTTGAACTGGCGGAGATTGTCCGTGCCCGTCGTCACGAGACCCCGGTCCCGGTAAATCTGGATGAC
TTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285EY61

Antitoxin

Source ID Structure
AlphaFold DB A0A554PKE4

References