90025

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4486993..4487354 Replicon chromosome
Accession NZ_CP025272
Organism Xanthomonas vasicola pv. vasculorum strain Xv1601

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag CXP37_RS20685 Protein ID WP_010374872.1
Coordinates 4486993..4487127 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag CXP37_RS20690 Protein ID WP_010374875.1
Coordinates 4487202..4487354 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXP37_RS20670 4484017..4485075 - 1059 WP_026112172.1 MBL fold metallo-hydrolase -
CXP37_RS20675 4485091..4486380 - 1290 WP_010374868.1 tryptophan--tRNA ligase -
CXP37_RS20680 4486552..4486761 - 210 WP_017117799.1 CsbD family protein -
CXP37_RS20685 4486993..4487127 - 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
CXP37_RS20690 4487202..4487354 - 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
CXP37_RS20695 4487462..4488385 - 924 WP_010379236.1 arginase -
CXP37_RS20700 4488708..4489160 + 453 WP_010374879.1 roadblock/LC7 domain-containing protein -
CXP37_RS20705 4489224..4489583 + 360 WP_010374881.1 hypothetical protein -
CXP37_RS20710 4489681..4490598 + 918 WP_017112292.1 hypothetical protein -
CXP37_RS20715 4490595..4491137 + 543 WP_010374885.1 GTPase -
CXP37_RS20725 4491616..4492299 + 684 WP_010374890.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T90025 WP_010374872.1 NZ_CP025272:c4487127-4486993 [Xanthomonas vasicola pv. vasculorum]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T90025 NZ_CP025272:c4487127-4486993 [Xanthomonas vasicola pv. vasculorum]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT90025 WP_010374875.1 NZ_CP025272:c4487354-4487202 [Xanthomonas vasicola pv. vasculorum]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT90025 NZ_CP025272:c4487354-4487202 [Xanthomonas vasicola pv. vasculorum]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGTAAGGACATGCAGGGTGCAGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References