Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1282436..1282935 Replicon chromosome
Accession NZ_CP025272
Organism Xanthomonas vasicola pv. vasculorum strain Xv1601

Toxin (Protein)


Gene name relE Uniprot ID A0A7C7F2G6
Locus tag CXP37_RS06055 Protein ID WP_010368415.1
Coordinates 1282436..1282687 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A836ZTX6
Locus tag CXP37_RS06060 Protein ID WP_010368416.1
Coordinates 1282684..1282935 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXP37_RS06030 1278084..1279439 + 1356 WP_017112158.1 aminodeoxychorismate synthase component I -
CXP37_RS06035 1279500..1280573 + 1074 WP_010368412.1 endolytic transglycosylase MltG -
CXP37_RS06040 1280570..1281529 + 960 WP_010368413.1 DNA polymerase III subunit delta' -
CXP37_RS06045 1281526..1281879 + 354 WP_003483889.1 PilZ domain-containing protein -
CXP37_RS06055 1282436..1282687 - 252 WP_010368415.1 Txe/YoeB family addiction module toxin Toxin
CXP37_RS06060 1282684..1282935 - 252 WP_010368416.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CXP37_RS06065 1283117..1283443 + 327 WP_010368417.1 hypothetical protein -
CXP37_RS06070 1283711..1285312 - 1602 WP_010368418.1 propionate catabolism operon regulatory protein PrpR -
CXP37_RS06075 1285458..1286354 + 897 WP_010368419.1 methylisocitrate lyase -
CXP37_RS06080 1286386..1286982 + 597 WP_010368420.1 DUF1003 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9719.15 Da        Isoelectric Point: 8.0471

>T90023 WP_010368415.1 NZ_CP025272:c1282687-1282436 [Xanthomonas vasicola pv. vasculorum]
VILQFSDNAWEDSLYWQQADKKILKRISELINAIQCDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAAEGILLIAQV
RYH

Download         Length: 252 bp

>T90023 NZ_CP025272:c1282687-1282436 [Xanthomonas vasicola pv. vasculorum]
GTGATCCTCCAGTTCTCGGATAATGCCTGGGAGGACTCTCTGTACTGGCAGCAGGCCGACAAGAAGATCCTCAAACGCAT
CAGCGAATTGATCAACGCCATTCAGTGCGATCCGTTCCAAGGCATCGGCAAACCCGAGCCACTGCGCCACGCGCTAGCGG
GTTATTGGTCGCGCCGCATCAATGACGAACACCGAATCGTCTACAAAGCCGCAGAAGGAATACTACTGATCGCCCAGGTG
CGTTATCACTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9224.66 Da        Isoelectric Point: 9.5902

>AT90023 WP_010368416.1 NZ_CP025272:c1282935-1282684 [Xanthomonas vasicola pv. vasculorum]
MNIITYSAARASLAETMDRVVNDHEPVIITRSGKRAVVMMSLDDYKAMKETAYLLRSPKSAQRLLESIAQLEAGRGKERG
LAE

Download         Length: 252 bp

>AT90023 NZ_CP025272:c1282935-1282684 [Xanthomonas vasicola pv. vasculorum]
ATGAATATCATCACCTACAGCGCCGCGCGCGCCTCTCTCGCAGAGACCATGGACCGCGTTGTCAACGACCACGAGCCAGT
GATCATCACGCGCAGCGGCAAACGAGCTGTCGTCATGATGTCCCTGGATGACTACAAGGCCATGAAGGAAACCGCCTACC
TGCTGCGCAGCCCGAAGAGTGCACAGCGCCTGCTGGAATCCATCGCCCAGCTTGAAGCCGGCCGCGGCAAGGAACGGGGA
CTGGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7C7F2G6

Antitoxin

Source ID Structure
AlphaFold DB A0A836ZTX6

References