Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1927880..1928151 Replicon chromosome
Accession NZ_CP025268
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1927918..1928021 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1927880..1928151 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXP41_RS10195 1925037..1926476 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CXP41_RS10200 1926594..1926830 + 237 WP_001295499.1 DUF1480 family protein -
CXP41_RS10205 1926935..1927126 + 192 WP_000457842.1 YebW family protein -
CXP41_RS10210 1927127..1927783 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1927880..1928151 + 272 - - Antitoxin
- 1927918..1928021 - 104 - - Toxin
CXP41_RS10215 1928179..1928520 - 342 WP_000976476.1 YebY family protein -
CXP41_RS10220 1928533..1929405 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
CXP41_RS10225 1929409..1929783 - 375 WP_000168747.1 CopC domain-containing protein YobA -
CXP41_RS10230 1929922..1930152 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CXP41_RS10235 1930254..1930910 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CXP41_RS10240 1930934..1931596 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T89997 NZ_CP025268:c1928021-1927918 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT89997 NZ_CP025268:1927880-1928151 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References