Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1168548..1169090 Replicon chromosome
Accession NZ_CP025228
Organism Actinomyces qiguomingii strain actinomyces sp. 410

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CWT10_RS04765 Protein ID WP_103063513.1
Coordinates 1168836..1169090 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CWT10_RS04760 Protein ID WP_103063512.1
Coordinates 1168548..1168799 (+) Length 84 a.a.

Genomic Context

CWT10_RS04750CWT10_RS04755CWT10_RS04760CWT10_RS04765CWT10_RS04775CWT10_RS04745CWT10_RS04770
Location: 1164249..1166069 (1821 bp)
Type: Others
Protein ID: WP_103063511.1
Location: 1166147..1168396 (2250 bp)
Type: Others
Protein ID: WP_103063568.1
Location: 1168548..1168799 (252 bp)
Type: Antitoxin
Protein ID: WP_103063512.1
Location: 1168836..1169090 (255 bp)
Type: Toxin
Protein ID: WP_103063513.1
Location: 1170301..1173801 (3501 bp)
Type: Others
Protein ID: WP_103063515.1
Location: 1163774..1163965 (192 bp)
Type: Others
Protein ID: WP_073327266.1
Location: 1169164..1169784 (621 bp)
Type: Others
Protein ID: WP_103063514.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CWT10_RS047451163774..1163965-192WP_073327266.150S ribosomal protein L28-
CWT10_RS047501164249..1166069+1821WP_103063511.1DAK2 domain-containing protein-
CWT10_RS047551166147..1168396+2250WP_103063568.1ATP-dependent DNA helicase RecG-
CWT10_RS047601168548..1168799+252WP_103063512.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
CWT10_RS047651168836..1169090+255WP_103063513.1Txe/YoeB family addiction module toxinToxin
CWT10_RS047701169164..1169784-621WP_103063514.116S rRNA (guanine(966)-N(2))-methyltransferase RsmD-
CWT10_RS047751170301..1173801+3501WP_103063515.1beta-galactosidase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9868.28 Da        Isoelectric Point: 8.0092

>T89917 WP_103063513.1 NZ_CP025228:1168836-1169090 [Actinomyces qiguomingii]
MRLVWDSSAWEDYCYWQTADRRTLKRINTLIAAALREPFAGIGKPEPLKYGAPGAWSRRITEEHRLVYLVDGEDLVILQA
RYHY

Download         Length: 255 bp

>T89917 NZ_CP025228:1168836-1169090 [Actinomyces qiguomingii]
ATGAGACTTGTCTGGGACTCCTCCGCCTGGGAGGACTACTGCTACTGGCAGACGGCCGACCGGCGCACGCTAAAACGCAT
CAACACACTCATCGCCGCCGCCCTGCGTGAACCCTTCGCCGGCATCGGCAAACCGGAACCGCTCAAGTACGGGGCTCCCG
GCGCCTGGTCCCGGCGCATCACCGAGGAGCATCGACTGGTCTACTTGGTGGACGGCGAGGACCTGGTCATCCTGCAGGCC
CGCTACCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9495.50 Da        Isoelectric Point: 4.6652

>AT89917 WP_103063512.1 NZ_CP025228:1168548-1168799 [Actinomyces qiguomingii]
MSISATEARRTLFPLIERVNADRDAVEIVSRHGNAVLMSADEYSAWQETAYLFRSPENARRLLDSYERARAGRVEAHELD
LDD

Download         Length: 252 bp

>AT89917 NZ_CP025228:1168548-1168799 [Actinomyces qiguomingii]
ATGTCGATCAGCGCAACCGAGGCGCGGCGCACCCTGTTCCCGCTGATCGAGCGAGTCAACGCGGACCGGGACGCCGTCGA
GATCGTCTCCCGCCACGGCAACGCCGTGCTCATGTCCGCCGACGAGTACTCGGCCTGGCAGGAGACGGCCTATCTCTTCC
GTTCACCCGAGAATGCCCGGCGCCTGCTGGACTCCTACGAGCGCGCCCGCGCAGGACGGGTCGAGGCCCACGAACTCGAC
CTCGACGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References