Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 903809..903954 Replicon chromosome
Accession NZ_CP025211
Organism Klebsiella pneumoniae strain HZW25

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 903845..903947 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 903809..903954 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CW753_RS04380 (CW753_04350) 898939..900999 + 2061 WP_004151449.1 oligopeptidase B -
CW753_RS04385 (CW753_04355) 901003..901662 - 660 WP_002911407.1 exodeoxyribonuclease X -
CW753_RS04390 (CW753_04360) 901741..901971 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CW753_RS04395 (CW753_04365) 902084..902458 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CW753_RS04400 (CW753_04370) 902462..903331 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
CW753_RS04405 (CW753_04375) 903348..903686 + 339 WP_002911404.1 YebY family protein -
- 903809..903954 - 146 - - Antitoxin
- 903845..903947 + 103 - - Toxin
CW753_RS28775 904323..904466 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CW753_RS04415 (CW753_04385) 904571..905539 - 969 WP_004151446.1 VirK/YbjX family protein -
CW753_RS04420 (CW753_04390) 905696..906349 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
CW753_RS04425 (CW753_04395) 906346..906537 - 192 WP_002911395.1 YebW family protein -
CW753_RS04430 (CW753_04400) 906635..906874 - 240 WP_002911393.1 YebV family protein -
CW753_RS04435 (CW753_04405) 906990..908422 - 1433 Protein_832 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T89870 NZ_CP025211:903845-903947 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT89870 NZ_CP025211:c903954-903809 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References