Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2051395..2051540 Replicon chromosome
Accession NZ_CP025146
Organism Klebsiella pneumoniae strain KP1766

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2051431..2051533 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2051395..2051540 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXB26_RS10570 2046525..2048585 + 2061 WP_004148850.1 oligopeptidase B -
CXB26_RS10575 2048589..2049248 - 660 WP_032435029.1 exodeoxyribonuclease X -
CXB26_RS10580 2049327..2049557 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CXB26_RS10585 2049670..2050044 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CXB26_RS10590 2050048..2050917 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
CXB26_RS10595 2050934..2051272 + 339 WP_002911404.1 YebY family protein -
- 2051395..2051540 - 146 - - Antitoxin
- 2051431..2051533 + 103 - - Toxin
CXB26_RS29480 2051908..2052051 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CXB26_RS10605 2052156..2053124 - 969 WP_004151446.1 VirK/YbjX family protein -
CXB26_RS10610 2053281..2053934 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
CXB26_RS10615 2053931..2054122 - 192 WP_002911395.1 YebW family protein -
CXB26_RS10620 2054220..2054459 - 240 WP_002911393.1 YebV family protein -
CXB26_RS10625 2054575..2056008 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1978694..2070003 91309


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T89836 NZ_CP025146:2051431-2051533 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT89836 NZ_CP025146:c2051540-2051395 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References