Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2059262..2059407 | Replicon | chromosome |
| Accession | NZ_CP025143 | ||
| Organism | Klebsiella pneumoniae strain NR5632 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2059298..2059400 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2059262..2059407 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CXB25_RS10585 | 2054392..2056452 | + | 2061 | WP_004148850.1 | oligopeptidase B | - |
| CXB25_RS10590 | 2056456..2057115 | - | 660 | WP_032435029.1 | exodeoxyribonuclease X | - |
| CXB25_RS10595 | 2057194..2057424 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| CXB25_RS10600 | 2057537..2057911 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| CXB25_RS10605 | 2057915..2058784 | + | 870 | WP_032435031.1 | copper homeostasis membrane protein CopD | - |
| CXB25_RS10610 | 2058801..2059139 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2059262..2059407 | - | 146 | - | - | Antitoxin |
| - | 2059298..2059400 | + | 103 | - | - | Toxin |
| CXB25_RS29445 | 2059775..2059918 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| CXB25_RS10620 | 2060023..2060991 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| CXB25_RS10625 | 2061148..2061801 | + | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| CXB25_RS10630 | 2061798..2061989 | - | 192 | WP_002911395.1 | YebW family protein | - |
| CXB25_RS10635 | 2062087..2062326 | - | 240 | WP_002911393.1 | YebV family protein | - |
| CXB25_RS10640 | 2062442..2063875 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T89815 NZ_CP025143:2059298-2059400 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT89815 NZ_CP025143:c2059407-2059262 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
