Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3396590..3396735 Replicon chromosome
Accession NZ_CP025140
Organism Klebsiella pneumoniae strain KP1768

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3396597..3396699 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3396590..3396735 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CXB24_RS17290 3392122..3393555 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CXB24_RS17295 3393671..3393910 + 240 WP_002911393.1 YebV family protein -
CXB24_RS17300 3394008..3394199 + 192 WP_002911395.1 YebW family protein -
CXB24_RS17305 3394196..3394849 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
CXB24_RS17310 3395006..3395974 + 969 WP_004151446.1 VirK/YbjX family protein -
CXB24_RS29510 3396079..3396222 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3396590..3396735 + 146 - - Antitoxin
- 3396597..3396699 - 103 - - Toxin
CXB24_RS17320 3396858..3397196 - 339 WP_002911404.1 YebY family protein -
CXB24_RS17325 3397213..3398082 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
CXB24_RS17330 3398086..3398460 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CXB24_RS17335 3398573..3398803 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CXB24_RS17340 3398882..3399541 + 660 WP_032435029.1 exodeoxyribonuclease X -
CXB24_RS17345 3399545..3401605 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T89796 NZ_CP025140:c3396699-3396597 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT89796 NZ_CP025140:3396590-3396735 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References