Detailed information of TA system TA089783

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 105910..107341
• Replicon: chromosome
• Accession: NZ_CP025115
• Organism: Alteromonas sp. MB-3u-76

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: CW735_RS00510
• Protein ID: WP_100970680.1
• Coordinates: 106442..107341 (+)
• Length: 300 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: A0A2K8XV75
• Locus tag: CW735_RS00505
• Protein ID: WP_071978202.1
• Coordinates: 105910..106449 (+)
• Length: 180 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CW735_RS00480	102296..103180	-	885	WP_100970678.1	acyl-CoA thioesterase II	-
CW735_RS00485	103498..104025	-	528	WP_100973134.1	DsrE family protein	-
CW735_RS00490	104095..104523	-	429	WP_100970679.1	rhodanese-like domain-containing protein	-
CW735_RS00495	104537..104956	-	420	WP_071978198.1	YeeE/YedE family protein	-
CW735_RS00500	104977..105405	-	429	WP_083595134.1	YeeE/YedE family protein	-
CW735_RS00505	105910..106449	+	540	WP_071978202.1	hypothetical protein	Antitoxin
CW735_RS00510	106442..107341	+	900	WP_100970680.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
CW735_RS00515	107362..108183	-	822	WP_100970681.1	MipA/OmpV family protein	-
CW735_RS00520	108730..109122	+	393	WP_071978205.1	OsmC family protein	-
CW735_RS00525	109193..110506	-	1314	WP_100970682.1	type II toxin-antitoxin system HipA family toxin	-
CW735_RS00530	110506..110772	-	267	WP_071978207.1	helix-turn-helix domain-containing protein	-
CW735_RS00535	111069..111677	+	609	Protein_99	hypothetical protein	-
CW735_RS19690	111979..112134	-	156	WP_198033582.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-253)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 300 a.a.
• Molecular weight: 34165.23 Da
• Isoelectric Point: 7.5474

>T89783 WP_100970680.1 NZ_CP025115:106442-107341 [Alteromonas sp. MB-3u-76]
MISDLVSQAIEKNPQLIGLEDVVEKEIVHHELLNILHKEGFLGHLTFIGGTALRMCYGSNRLSEDLDFTGGAHFSPKDFS
SLSADIESHLQNKFMLDVNVREPLIDRGDTSTWKVTIIKNPKRPDLPSQKMHIDICRYDSFDKVQRPAKNFYDINSPIEG
LPIPVQSSKEILADKLIALAFRERRIKPRDVWDLAWLSQQNVPIEASLVKKKLVMRGKTQKGFLKNLQIHSESILASDET
KLDFEREMLRFVPKDIRERTLNRKEFWPYVGETIASQIETIGSALNRNSTDGHGSNMKM

Nucleotide

• Length: 900 bp

>T89783 NZ_CP025115:106442-107341 [Alteromonas sp. MB-3u-76]
ATGATTAGTGATTTGGTCTCTCAGGCGATTGAGAAGAACCCTCAATTAATAGGGTTGGAAGATGTTGTAGAAAAAGAGAT
TGTGCATCATGAGTTGCTTAACATTCTGCATAAAGAAGGGTTTCTGGGACATCTCACTTTTATCGGCGGAACGGCTTTAC
GTATGTGCTATGGCTCTAATCGCTTGTCAGAAGACTTGGACTTCACAGGAGGGGCGCATTTTTCACCTAAAGACTTCTCT
TCGTTATCTGCCGATATCGAGTCGCACTTGCAAAACAAATTCATGCTAGACGTTAATGTGCGCGAGCCTTTAATAGACCG
CGGTGACACATCAACCTGGAAAGTGACTATTATCAAAAACCCTAAGCGGCCAGACTTACCTTCACAGAAGATGCACATCG
ATATTTGCCGCTATGATTCGTTTGATAAGGTTCAGCGCCCTGCTAAAAATTTTTATGACATAAATTCGCCTATTGAAGGC
TTACCAATTCCGGTACAAAGCAGTAAAGAGATACTGGCCGACAAGCTGATTGCGTTAGCGTTTCGAGAGCGTCGGATAAA
ACCACGGGACGTGTGGGACTTAGCATGGCTAAGCCAACAGAACGTTCCGATTGAAGCTTCACTGGTAAAAAAGAAGCTTG
TAATGCGTGGTAAAACTCAGAAAGGTTTTCTCAAAAATCTACAGATACACAGTGAATCCATTCTGGCGTCGGATGAGACG
AAATTAGACTTTGAAAGAGAAATGTTACGATTTGTCCCTAAAGATATCCGTGAACGTACCTTAAATCGCAAGGAGTTTTG
GCCATATGTGGGTGAAACGATAGCCTCACAAATCGAGACAATTGGATCGGCGCTGAATAGAAATTCCACAGATGGCCACG
GTTCGAACATGAAGATGTAG

Antitoxin

Protein

• Length: 180 a.a.
• Molecular weight: 20534.47 Da
• Isoelectric Point: 10.1355

>AT89783 WP_071978202.1 NZ_CP025115:105910-106449 [Alteromonas sp. MB-3u-76]
MSFALKVTSTLHKAIKNGHFGIFTTHDIALSLLESADDNFRKKLSKGVSRGWLLKVCRDMYALPSDEPTKRGVLEYIASR
LHWNKFIYVSLESELSRQGVISQIPFSYLTVMTQGRSGKIETRYGTIEFTHTNRKNRTAEDVYYDPDTRIFRARAKRAIA
DLKRVGRNVDMINEEAVND

Nucleotide

• Length: 540 bp

>AT89783 NZ_CP025115:105910-106449 [Alteromonas sp. MB-3u-76]
ATGAGTTTTGCTCTTAAGGTTACTAGTACACTACACAAAGCCATAAAAAACGGGCACTTCGGTATATTTACGACTCACGA
TATTGCATTATCTTTATTAGAAAGCGCTGATGATAATTTTCGAAAAAAACTTTCTAAAGGTGTTTCAAGAGGGTGGCTAT
TGAAAGTATGCCGAGACATGTATGCATTGCCCAGTGATGAGCCTACAAAGCGAGGCGTGCTTGAATATATTGCATCGCGC
CTGCATTGGAATAAATTCATATACGTCAGTCTCGAAAGTGAGCTCTCAAGGCAAGGAGTAATATCGCAAATTCCTTTTAG
TTACCTTACCGTTATGACACAAGGTCGAAGTGGGAAAATAGAGACGCGATATGGAACCATTGAGTTTACGCATACCAATC
GAAAAAACCGAACGGCAGAAGATGTGTATTATGATCCAGATACACGAATTTTCCGGGCCAGAGCCAAGCGCGCAATAGCT
GATTTAAAGCGGGTCGGGAGAAATGTGGATATGATAAATGAAGAGGCAGTGAATGATTAG

Structures

Antitoxin

• AlphaFold DB: A0A2K8XV75