Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2130851..2130996 Replicon chromosome
Accession NZ_CP025037
Organism Klebsiella pneumoniae strain NU-CRE047

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2130887..2130989 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2130851..2130996 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CWQ24_RS10620 2125981..2128041 + 2061 WP_004151449.1 oligopeptidase B -
CWQ24_RS10625 2128045..2128704 - 660 WP_002911407.1 exodeoxyribonuclease X -
CWQ24_RS10630 2128783..2129013 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CWQ24_RS10635 2129126..2129500 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CWQ24_RS10640 2129504..2130373 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
CWQ24_RS10645 2130390..2130728 + 339 WP_002911404.1 YebY family protein -
- 2130851..2130996 - 146 - - Antitoxin
- 2130887..2130989 + 103 - - Toxin
CWQ24_RS31720 2131364..2131507 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CWQ24_RS10655 2131612..2132580 - 969 WP_004151446.1 VirK/YbjX family protein -
CWQ24_RS10660 2132737..2133390 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
CWQ24_RS10665 2133387..2133578 - 192 WP_002911395.1 YebW family protein -
CWQ24_RS10670 2133676..2133915 - 240 WP_002911393.1 YebV family protein -
CWQ24_RS10675 2134031..2135464 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T89566 NZ_CP025037:2130887-2130989 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT89566 NZ_CP025037:c2130996-2130851 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References