Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3634884..3636415 Replicon chromosome
Accession NZ_CP025030
Organism Achromobacter spanius strain DSM 23806

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag CVS48_RS16495 Protein ID WP_157814471.1
Coordinates 3635504..3636415 (+) Length 304 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag CVS48_RS16490 Protein ID WP_100855374.1
Coordinates 3634884..3635498 (+) Length 205 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVS48_RS16480 3630229..3630684 - 456 WP_100855372.1 GNAT family N-acetyltransferase -
CVS48_RS16485 3630737..3634792 - 4056 WP_100855373.1 helix-turn-helix domain-containing protein -
CVS48_RS16490 3634884..3635498 + 615 WP_100855374.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
CVS48_RS16495 3635504..3636415 + 912 WP_157814471.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CVS48_RS16500 3636649..3637446 + 798 WP_100855376.1 GntR family transcriptional regulator -
CVS48_RS16505 3637465..3638670 + 1206 WP_100855377.1 ABC transporter substrate-binding protein -
CVS48_RS16510 3638680..3639552 + 873 WP_100855378.1 branched-chain amino acid ABC transporter permease -
CVS48_RS16515 3639555..3640523 + 969 WP_100855379.1 branched-chain amino acid ABC transporter permease -
CVS48_RS16520 3640516..3641271 + 756 WP_100855380.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3610090..3636415 26325


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-267)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(10-55)


Sequences

Toxin        


Download         Length: 304 a.a.        Molecular weight: 34299.45 Da        Isoelectric Point: 7.3840

>T89538 WP_157814471.1 NZ_CP025030:3635504-3636415 [Achromobacter spanius]
MNPAFSIRARLLTHAKRHGDDFQRVLTRYAIERLLFRLSQTKVGEHYVLKGAMLFVTWPRYVFRPTGDLDLLGQGNSEPA
ALVELFTRICQVECVADGIVFDAAMVRVEAVREADKYHGSRISLAADLAGARIPVQIDVGFGDRVYPEPKREIFPSLVPD
VPHASILMYPPETVVAEKFEAMIRFGETNTRIKDYYDVWVTTRIFPFDMANVVEAVGGTLRRRETAIPTEMPMGLTSTFA
AIVDERGLWSGFLRRTSPTLTPPSFPDLQSELRSFFRLVIEGLNMSEGARGVWDTDGRVWRNR

Download         Length: 912 bp

>T89538 NZ_CP025030:3635504-3636415 [Achromobacter spanius]
ATGAATCCCGCCTTCTCGATACGTGCAAGGCTGCTCACCCATGCCAAACGACACGGGGACGACTTTCAGCGGGTGCTGAC
TCGTTACGCCATTGAGCGACTGCTGTTCCGCCTTAGTCAGACGAAGGTGGGAGAACATTACGTGCTGAAGGGTGCAATGT
TGTTCGTGACTTGGCCCAGATACGTCTTCCGCCCGACCGGCGATCTGGATCTATTGGGGCAGGGAAATTCAGAACCTGCG
GCTCTCGTGGAACTCTTCACTCGCATCTGCCAGGTCGAATGCGTCGCCGACGGTATTGTTTTTGATGCGGCCATGGTGAG
GGTCGAGGCGGTTCGCGAAGCCGACAAGTACCACGGATCTCGCATTAGCCTCGCCGCAGACTTGGCGGGGGCAAGGATCC
CAGTCCAGATTGACGTCGGTTTCGGTGACCGAGTCTATCCGGAACCGAAGCGCGAAATATTTCCGAGCTTAGTGCCTGAC
GTCCCGCATGCCAGCATTTTGATGTATCCACCCGAGACGGTAGTCGCCGAGAAATTTGAGGCGATGATCAGGTTCGGCGA
AACCAATACCCGAATTAAGGACTATTACGACGTATGGGTCACCACTAGGATCTTTCCGTTCGATATGGCCAATGTAGTCG
AGGCCGTCGGTGGAACTCTTCGGCGCCGCGAGACGGCTATTCCGACGGAAATGCCGATGGGGCTTACCAGTACGTTTGCC
GCGATTGTTGATGAACGTGGTCTGTGGTCGGGTTTTCTACGTCGGACCTCCCCAACTCTAACGCCGCCGTCGTTTCCAGA
CCTTCAATCCGAATTGCGAAGTTTTTTCCGCTTAGTTATTGAGGGCCTCAATATGTCCGAAGGTGCTCGAGGAGTGTGGG
ACACGGACGGTAGAGTTTGGCGGAACCGTTAG

Antitoxin


Download         Length: 205 a.a.        Molecular weight: 22556.13 Da        Isoelectric Point: 10.0411

>AT89538 WP_100855374.1 NZ_CP025030:3634884-3635498 [Achromobacter spanius]
MSEYPISNRERVLQLVRDRGIARARDLTAAGIPLAYLKRLTDSGDLIRLGRGLYQTPDRVGEDAAHDLAEAARRVPKGVI
SLISALRWHEVTTQLPNAVWMTIPHKSRVPKSTGLRLEIVRATGETLTAGVEYVDVEGVAVPVYCVAKTVADCFKHRRHV
GEDVAIEALRDALHQRKATPSDLMKFAAINRVAGLMAPYIRAMQ

Download         Length: 615 bp

>AT89538 NZ_CP025030:3634884-3635498 [Achromobacter spanius]
ATGTCCGAATATCCCATTTCTAATCGCGAACGAGTCCTTCAGCTAGTGAGGGACAGAGGAATCGCGCGCGCGCGTGACCT
TACGGCTGCGGGCATTCCCCTCGCATATCTAAAACGCCTGACCGACAGTGGCGACCTTATCCGTTTGGGTCGCGGTCTCT
ACCAAACACCGGATCGCGTCGGCGAAGATGCCGCCCATGATCTCGCCGAGGCGGCCCGCCGAGTGCCTAAGGGAGTCATT
AGCCTGATCAGTGCTCTTCGCTGGCACGAAGTGACGACGCAACTGCCGAATGCCGTCTGGATGACCATTCCCCACAAGTC
CCGTGTACCTAAGTCAACCGGTCTGAGACTAGAAATTGTGCGCGCCACGGGCGAGACCCTGACCGCCGGCGTCGAATACG
TCGACGTGGAAGGGGTGGCTGTGCCCGTTTACTGCGTTGCCAAGACGGTGGCAGATTGTTTCAAGCATCGGCGTCATGTA
GGTGAGGATGTGGCTATCGAAGCCCTGCGTGACGCCCTGCATCAGCGCAAGGCTACCCCTAGTGACCTTATGAAATTTGC
TGCGATTAACCGGGTCGCCGGTCTAATGGCACCGTATATCAGGGCGATGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References