Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 298541..299114 Replicon chromosome
Accession NZ_CP025030
Organism Achromobacter spanius strain DSM 23806

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CVS48_RS01505 Protein ID WP_100852951.1
Coordinates 298541..298918 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CVS48_RS01510 Protein ID WP_100852952.1
Coordinates 298905..299114 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVS48_RS01480 295319..296212 + 894 WP_100852947.1 septum site-determining protein MinC -
CVS48_RS01485 296366..297181 + 816 WP_100852948.1 septum site-determining protein MinD -
CVS48_RS01490 297185..297442 + 258 WP_050448917.1 cell division topological specificity factor MinE -
CVS48_RS01495 297518..297742 - 225 WP_100852949.1 glycine zipper 2TM domain-containing protein -
CVS48_RS01500 297932..298465 - 534 WP_100852950.1 isochorismatase family protein -
CVS48_RS01505 298541..298918 - 378 WP_100852951.1 type II toxin-antitoxin system VapC family toxin Toxin
CVS48_RS01510 298905..299114 - 210 WP_100852952.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
CVS48_RS01515 299509..301182 - 1674 WP_100852953.1 energy-dependent translational throttle protein EttA -
CVS48_RS01520 301269..302195 - 927 WP_100852954.1 DMT family transporter -
CVS48_RS01525 302513..303034 + 522 WP_100852955.1 hypothetical protein -
CVS48_RS01530 303111..304100 - 990 WP_100852956.1 dipeptide ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-44)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13879.20 Da        Isoelectric Point: 6.9225

>T89534 WP_100852951.1 NZ_CP025030:c298918-298541 [Achromobacter spanius]
MILVDTSIWIDHLGASEPRLEQLLHNEFVLMHPFIVGELALGSLNKRDMVLGALTLLPQAVRASHDEAIHFLHAERLFGK
GIGYVDLHLLASTRLTPGASLWTKDKRLGSLAKTLNLSVEPPLYH

Download         Length: 378 bp

>T89534 NZ_CP025030:c298918-298541 [Achromobacter spanius]
ATGATCTTGGTTGACACGTCGATCTGGATCGATCATCTGGGGGCAAGCGAACCCCGGCTTGAACAGTTGCTCCACAATGA
ATTTGTCCTGATGCACCCGTTCATCGTTGGCGAACTGGCGCTCGGATCGCTGAATAAGCGGGACATGGTGTTGGGCGCAC
TGACGCTTTTGCCACAGGCGGTTCGGGCGAGCCACGACGAGGCAATCCACTTTCTTCATGCCGAACGGCTATTTGGAAAA
GGCATCGGCTATGTCGACCTGCATCTGCTTGCATCGACCCGCCTGACGCCCGGTGCTTCGCTGTGGACCAAAGACAAGCG
GCTGGGATCTCTTGCCAAGACCTTGAACCTGTCTGTCGAGCCCCCGCTATATCATTGA

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7578.67 Da        Isoelectric Point: 9.8652

>AT89534 WP_100852952.1 NZ_CP025030:c299114-298905 [Achromobacter spanius]
MRTTVTLDDDLLEKARIYTGIQETSALVQQALTNLVQKEAAKRLAKLGGSSPKLKPTPRRQTETPDDLG

Download         Length: 210 bp

>AT89534 NZ_CP025030:c299114-298905 [Achromobacter spanius]
ATGCGTACCACAGTGACGCTCGATGACGATTTGCTCGAGAAAGCGCGAATCTATACGGGCATACAGGAAACCTCTGCGCT
TGTGCAGCAGGCGCTGACGAACCTGGTGCAGAAAGAGGCGGCCAAGCGCCTGGCCAAACTGGGCGGCAGTTCACCCAAAT
TGAAGCCGACGCCACGGCGGCAAACGGAGACACCCGATGATCTTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References