Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 85511..86307 Replicon plasmid pRLN4
Accession NZ_CP025016
Organism Rhizobium leguminosarum strain Norway

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CUJ84_RS35315 Protein ID WP_105010087.1
Coordinates 85804..86307 (+) Length 168 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag CUJ84_RS35310 Protein ID WP_105010086.1
Coordinates 85511..85807 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUJ84_RS35295 80632..81678 + 1047 WP_105010083.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
CUJ84_RS35300 82233..83243 + 1011 WP_105010084.1 DUF4105 domain-containing protein -
CUJ84_RS35305 83417..85174 + 1758 WP_105010085.1 DUF521 domain-containing protein -
CUJ84_RS35310 85511..85807 + 297 WP_105010086.1 DUF1778 domain-containing protein Antitoxin
CUJ84_RS35315 85804..86307 + 504 WP_105010087.1 GNAT family N-acetyltransferase Toxin
CUJ84_RS35320 86490..87992 - 1503 WP_158687012.1 MFS transporter -
CUJ84_RS35325 87958..88854 + 897 WP_105010089.1 LysR family transcriptional regulator -
CUJ84_RS35330 89164..90255 - 1092 WP_105010090.1 GDP-L-fucose synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd 1..354350 354350


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-142)

Antitoxin

Vibrio phage ICP1, Orf50

(8-97)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 17878.49 Da        Isoelectric Point: 8.1063

>T89516 WP_105010087.1 NZ_CP025016:85804-86307 [Rhizobium leguminosarum]
VTLSAPAPLADHHELAEFGSGVPELDGWLRRRARANQAGGASRTFVVCEGDRVIAYYALASGAVKQPEAPGRFRRNMPDP
IPVAVLGRLAIDQSHQGRGIGRALVRDAGLRLLNAAEILGIRGVLVHAISDDVRAFYEAVGFLPSPSDPMMLMVGLHDLN
RALNSQP

Download         Length: 504 bp

>T89516 NZ_CP025016:85804-86307 [Rhizobium leguminosarum]
GTGACCCTCAGCGCACCGGCACCACTGGCCGATCATCACGAACTGGCCGAATTCGGTTCCGGCGTACCCGAACTAGATGG
CTGGCTGCGTCGCCGCGCCCGCGCAAATCAGGCAGGCGGCGCATCGCGCACCTTCGTGGTGTGCGAGGGAGACCGGGTCA
TCGCCTACTATGCGCTCGCCTCGGGTGCGGTGAAGCAGCCGGAAGCACCTGGCCGGTTTCGCCGCAACATGCCTGATCCG
ATTCCGGTTGCCGTGCTTGGCCGCCTCGCCATTGATCAGTCCCACCAGGGGCGCGGTATCGGCAGGGCTTTAGTGCGCGA
CGCAGGCCTGCGCCTGCTCAATGCCGCAGAAATCCTCGGAATCCGGGGCGTGCTGGTGCATGCGATTTCTGATGATGTGC
GAGCCTTCTATGAGGCGGTCGGCTTCCTGCCTTCGCCATCCGACCCCATGATGCTGATGGTCGGGTTGCATGATCTCAAC
AGAGCGCTAAACTCTCAACCGTAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11155.70 Da        Isoelectric Point: 7.0161

>AT89516 WP_105010086.1 NZ_CP025016:85511-85807 [Rhizobium leguminosarum]
MPASHTPKSRDASVPLNMRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTIFTVSPEIYAEYLTRLDAPAQ
PNERLNRTMSTKAPWDEA

Download         Length: 297 bp

>AT89516 NZ_CP025016:85511-85807 [Rhizobium leguminosarum]
ATGCCCGCCTCGCACACGCCTAAAAGCCGGGACGCAAGCGTGCCGCTCAATATGCGCATCAAGCCTGCGACCCGCAACCT
GATTGACCGCGCCGCCGAGCTGCTTGGCAAAACCCGCACGGATTTCATGCTGGAGGCTTCCGAGCGCCGCGCCGAGGAAG
TGCTGCTCGACCGTACCATATTCACGGTCAGCCCCGAAATCTATGCCGAATACCTAACCCGCCTCGACGCGCCCGCCCAG
CCCAATGAGCGCCTGAATCGCACCATGTCGACCAAAGCGCCATGGGATGAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References