Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii(toxin)
Location 543054..544530 Replicon plasmid pRLN3
Accession NZ_CP025015
Organism Rhizobium leguminosarum strain Norway

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag CUJ84_RS34860 Protein ID WP_105010000.1
Coordinates 543054..543920 (-) Length 289 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag CUJ84_RS34865 Protein ID WP_105010001.1
Coordinates 543913..544530 (-) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUJ84_RS34845 540570..541136 + 567 WP_105009997.1 conjugative transfer signal peptidase TraF -
CUJ84_RS34850 541126..542289 + 1164 WP_105009998.1 conjugal transfer protein TraB -
CUJ84_RS34855 542306..542923 + 618 WP_105009999.1 conjugal transfer protein TraH -
CUJ84_RS34860 543054..543920 - 867 WP_105010000.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CUJ84_RS34865 543913..544530 - 618 WP_105010001.1 transcriptional regulator Antitoxin
CUJ84_RS34870 544859..545062 - 204 WP_018482036.1 DUF433 domain-containing protein -
CUJ84_RS34875 545114..545326 - 213 WP_018482035.1 helix-turn-helix transcriptional regulator -
CUJ84_RS34880 545532..545855 + 324 WP_018482034.1 transcriptional repressor TraM -
CUJ84_RS34885 545859..546563 - 705 WP_105010002.1 autoinducer binding domain-containing protein -
CUJ84_RS34890 546875..548173 - 1299 WP_018482032.1 IncP-type conjugal transfer protein TrbI -
CUJ84_RS34895 548175..548618 - 444 WP_018482031.1 lipoprotein -
CUJ84_RS34900 548622..549434 - 813 WP_020572024.1 P-type conjugative transfer protein TrbG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..557386 557386


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-263)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 289 a.a.        Molecular weight: 32095.78 Da        Isoelectric Point: 5.1954

>T89515 WP_105010000.1 NZ_CP025015:c543920-543054 [Rhizobium leguminosarum]
MAKDIGNVGASVRAHLLQLAKASGQSFDLVLTRFALERLLFRLSQSPHAGRFVLKGAMLMMSWFDNPHRGTRDLDLLGFG
DPSPDPMLETFREILAQEADDGVTFDADTLHVDRIREALDYGGLRLRVIASISGARINLTIDIGFGDALEPGVEVLDYPS
MLDFPMPRLRAYARETVIAEKFPAMVMLGRVNSRMKDFYDIWILSRSFDFSDDRLARAIAATFDRRATSIPIDLPDALTD
AFAKDQQKQRQWRAFVEGVAHNPGDLTDVIAEIATFLMPHAVAAARLD

Download         Length: 867 bp

>T89515 NZ_CP025015:c543920-543054 [Rhizobium leguminosarum]
ATGGCTAAAGACATCGGAAACGTCGGCGCCTCGGTGCGCGCCCACCTGTTGCAACTCGCCAAGGCAAGCGGGCAAAGCTT
CGATCTGGTCCTGACGCGTTTTGCTCTTGAACGGTTATTGTTCCGGCTTAGCCAGTCGCCCCACGCCGGTCGCTTCGTTC
TAAAGGGGGCGATGTTGATGATGAGTTGGTTCGACAATCCGCACCGAGGCACGCGCGACCTCGATCTTTTGGGTTTCGGT
GATCCGAGTCCGGACCCGATGCTTGAGACATTTCGGGAAATTCTGGCGCAAGAGGCCGACGATGGCGTTACGTTTGACGC
TGATACGCTGCATGTGGATCGTATTCGCGAGGCATTGGATTATGGTGGGCTCAGGCTGCGGGTGATCGCTTCGATCAGCG
GAGCCCGGATCAACCTGACGATCGACATCGGTTTTGGCGATGCGCTTGAGCCTGGGGTGGAGGTTTTGGATTATCCTTCT
ATGCTCGATTTTCCGATGCCGCGGCTTCGGGCCTATGCGCGAGAAACGGTCATTGCCGAGAAGTTCCCGGCAATGGTGAT
GCTGGGGCGAGTAAACAGCCGCATGAAGGATTTCTACGACATCTGGATCCTCAGCAGGTCTTTCGACTTCAGCGATGATC
GGCTGGCGCGCGCAATAGCCGCTACCTTTGATCGCCGCGCGACATCGATCCCCATTGACCTCCCCGACGCCCTAACGGAC
GCCTTTGCCAAGGACCAGCAAAAGCAGCGGCAATGGCGAGCTTTCGTTGAAGGCGTTGCACACAATCCTGGCGATCTGAC
AGACGTCATCGCGGAGATTGCCACATTCCTGATGCCGCACGCGGTTGCGGCTGCGAGGCTGGACTAG

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22296.78 Da        Isoelectric Point: 10.2141

>AT89515 WP_105010001.1 NZ_CP025015:c544530-543913 [Rhizobium leguminosarum]
MPGSVTQRQIARTVLTERGIARLVELRNAGVTAATMSRMDRDGEVLRLARGLYQLPDAQLDVNHSLAEVAKRAPKAVICL
VSALAFHGLTDQLPGQIWLAIGRKDWAPKLDGPALRIVRFTDSLLNESVETHVIEGVPVRVFGIAKTIADCFRYRNKIGL
SVAIEGLQEALRQRRATPGEIANQAERGGVGSVIRPYLEALTANG

Download         Length: 618 bp

>AT89515 NZ_CP025015:c544530-543913 [Rhizobium leguminosarum]
ATGCCCGGTTCCGTCACGCAACGCCAAATCGCCCGGACCGTGCTAACTGAGCGCGGAATAGCACGCTTGGTCGAACTGCG
GAACGCAGGTGTGACGGCTGCCACCATGAGCCGAATGGATCGAGATGGTGAAGTGCTCCGGCTTGCCCGCGGTCTTTATC
AACTTCCTGATGCGCAGCTCGACGTCAACCACAGCCTGGCGGAGGTTGCCAAACGCGCGCCCAAAGCCGTCATCTGCCTC
GTTTCGGCATTGGCGTTCCACGGCCTGACAGATCAGCTCCCCGGACAAATCTGGCTTGCCATAGGCCGTAAGGACTGGGC
TCCGAAACTGGACGGGCCCGCTCTGCGCATCGTGCGTTTCACAGACAGCCTTCTCAACGAAAGCGTCGAAACCCATGTCA
TTGAAGGCGTTCCTGTGAGGGTCTTTGGAATTGCCAAGACAATTGCCGATTGCTTTCGCTATCGCAACAAGATCGGCCTT
TCGGTAGCGATAGAAGGGCTGCAGGAGGCGCTGCGGCAACGAAGGGCTACTCCTGGCGAGATCGCCAACCAGGCCGAACG
CGGTGGCGTCGGATCGGTGATCCGGCCGTATCTCGAGGCGCTGACCGCCAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References