Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2885975..2886648 Replicon chromosome
Accession NZ_CP025012
Organism Rhizobium leguminosarum strain Norway

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CUJ84_RS14640 Protein ID WP_105006746.1
Coordinates 2885975..2886388 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CUJ84_RS14645 Protein ID WP_105006747.1
Coordinates 2886385..2886648 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUJ84_RS14630 2883404..2884615 - 1212 WP_105006744.1 efflux RND transporter periplasmic adaptor subunit -
CUJ84_RS14635 2884883..2885797 - 915 WP_105006745.1 adenylate/guanylate cyclase domain-containing protein -
CUJ84_RS14640 2885975..2886388 - 414 WP_105006746.1 type II toxin-antitoxin system VapC family toxin Toxin
CUJ84_RS14645 2886385..2886648 - 264 WP_105006747.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CUJ84_RS14650 2886776..2888323 - 1548 WP_105006748.1 SpoVR family protein -
CUJ84_RS14655 2888320..2889594 - 1275 WP_105006749.1 YeaH/YhbH family protein -
CUJ84_RS14660 2889607..2891550 - 1944 WP_018242831.1 PrkA family serine protein kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(9-54)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15153.52 Da        Isoelectric Point: 4.9436

>T89508 WP_105006746.1 NZ_CP025012:c2886388-2885975 [Rhizobium leguminosarum]
MTAWMLDTNMVSHVIKGDRPEIIERLAALPMEDIVISSITEGELLYGLAKRGYPKALSERISQFLLRVDVLPWDHDVTRT
YGDLRVACEAKGVTLAPLDMMIAAHAVATAATLVTRDKAFARVSEPLKVDDWTNEGS

Download         Length: 414 bp

>T89508 NZ_CP025012:c2886388-2885975 [Rhizobium leguminosarum]
ATGACAGCCTGGATGCTCGATACCAATATGGTGAGCCATGTCATCAAGGGCGATCGGCCGGAGATCATCGAAAGGTTGGC
CGCGCTTCCGATGGAAGACATCGTCATCTCATCGATCACCGAAGGGGAGTTGCTCTACGGTCTTGCTAAGCGAGGCTATC
CGAAGGCGCTGTCAGAACGGATCAGCCAATTCCTGCTCCGGGTCGACGTTCTCCCTTGGGATCACGATGTCACGCGAACT
TATGGCGACCTGCGCGTTGCCTGCGAAGCCAAAGGGGTGACTCTGGCGCCCCTCGATATGATGATTGCCGCTCATGCCGT
TGCAACTGCCGCAACCCTCGTCACGCGCGACAAGGCTTTTGCTCGCGTTTCGGAGCCTTTGAAGGTCGATGACTGGACGA
ATGAAGGAAGCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10072.18 Da        Isoelectric Point: 5.1734

>AT89508 WP_105006747.1 NZ_CP025012:c2886648-2886385 [Rhizobium leguminosarum]
MATRTAKIFTTGRSQAVRLPAEFRFEGSEVFVRRDPKTGDVILSRKPDSWDGLFELYGKDQVPDDFLGPDDRRQPSHDRD
PFEGWKE

Download         Length: 264 bp

>AT89508 NZ_CP025012:c2886648-2886385 [Rhizobium leguminosarum]
ATGGCAACGAGAACAGCCAAGATTTTTACGACCGGCCGCAGCCAGGCGGTCAGGCTCCCTGCGGAGTTCCGCTTCGAGGG
GAGCGAGGTGTTCGTCCGTCGTGATCCGAAGACTGGCGATGTCATTCTGTCACGCAAGCCGGATTCATGGGATGGCCTCT
TTGAACTCTATGGCAAGGATCAGGTTCCGGACGATTTCCTGGGGCCAGACGACCGTCGCCAGCCTTCGCATGATCGTGAT
CCATTCGAGGGCTGGAAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References