Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2012418..2012563 | Replicon | chromosome |
| Accession | NZ_CP025008 | ||
| Organism | Klebsiella pneumoniae strain AUSMDU00008119 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2012454..2012556 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2012418..2012563 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CWN89_RS10140 | 2007548..2009608 | + | 2061 | WP_032422099.1 | oligopeptidase B | - |
| CWN89_RS10145 | 2009612..2010271 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| CWN89_RS10150 | 2010350..2010580 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| CWN89_RS10155 | 2010693..2011067 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| CWN89_RS10160 | 2011071..2011940 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| CWN89_RS10165 | 2011957..2012295 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2012418..2012563 | - | 146 | - | - | Antitoxin |
| - | 2012454..2012556 | + | 103 | - | - | Toxin |
| CWN89_RS29555 | 2012931..2013074 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| CWN89_RS10175 | 2013179..2014147 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| CWN89_RS10180 | 2014304..2014957 | + | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| CWN89_RS10185 | 2014954..2015145 | - | 192 | WP_002911395.1 | YebW family protein | - |
| CWN89_RS10190 | 2015243..2015482 | - | 240 | WP_002911393.1 | YebV family protein | - |
| CWN89_RS10195 | 2015598..2017031 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T89492 NZ_CP025008:2012454-2012556 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT89492 NZ_CP025008:c2012563-2012418 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
