89452

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 422495..423330 Replicon chromosome
Accession NZ_CP025003
Organism Dickeya fangzhongdai strain DSM 101947

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag CVE23_RS01970 Protein ID WP_100848750.1
Coordinates 422956..423330 (+) Length 125 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag CVE23_RS01965 Protein ID WP_100848749.1
Coordinates 422495..422956 (+) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVE23_RS01955 418341..418634 + 294 WP_012883104.1 type I-E CRISPR-associated endoribonuclease Cas2 -
CVE23_RS01960 420271..421947 - 1677 WP_100848748.1 MCP four helix bundle domain-containing protein -
CVE23_RS01965 422495..422956 + 462 WP_100848749.1 helix-turn-helix domain-containing protein Antitoxin
CVE23_RS01970 422956..423330 + 375 WP_100848750.1 toxin PIN Toxin
CVE23_RS01975 423554..424006 + 453 WP_038917619.1 YhbP family protein -
CVE23_RS01980 424118..424582 - 465 WP_100848751.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
CVE23_RS01985 424681..426819 - 2139 WP_100848752.1 anaerobic ribonucleoside-triphosphate reductase -
CVE23_RS01990 427199..428107 + 909 WP_100848753.1 homocysteine S-methyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

SinI-like, DNA-binding domain

(84-131)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 13806.82 Da        Isoelectric Point: 4.6730

>T89452 WP_100848750.1 NZ_CP025003:422956-423330 [Dickeya fangzhongdai]
MNQAIPDAMITGFEALIPGITLPDPDDQHVVAAAIRSNAEIIVTFNLKDFPHPEIDNFGIEALHPDDFITDLLDLNQALV
LSAVSRQRHSMRKPPKSVDEYLDALLRQSLPQTVKELSKFHALI

Download         Length: 375 bp

>T89452 NZ_CP025003:422956-423330 [Dickeya fangzhongdai]
ATGAATCAGGCTATTCCTGATGCGATGATTACTGGGTTTGAAGCGCTCATTCCAGGCATCACGCTCCCTGATCCTGATGA
TCAGCATGTGGTTGCAGCCGCCATTCGCAGTAACGCTGAAATCATCGTTACGTTTAACCTGAAAGATTTTCCCCATCCCG
AGATCGATAACTTTGGCATTGAAGCGCTACACCCGGATGATTTCATCACAGACCTGCTCGATTTGAATCAGGCGCTTGTG
TTATCCGCAGTAAGCAGGCAGCGTCACAGCATGAGAAAACCGCCTAAATCGGTTGATGAGTATCTTGATGCGTTACTCCG
GCAGAGCTTACCGCAAACAGTAAAAGAATTGAGTAAATTCCACGCCCTGATTTAG

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 16883.25 Da        Isoelectric Point: 6.2221

>AT89452 WP_100848749.1 NZ_CP025003:422495-422956 [Dickeya fangzhongdai]
MTNSILDSLSLPAPGEIEAAVRGQRELAAYLSTKMETQKISIQDADNNTRQVELPTSALTLLMSILGELAVGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEDGKLPFHKTGRHRRVLFADLMDYKHQRDNESSRAMQALADHGQELGLY

Download         Length: 462 bp

>AT89452 NZ_CP025003:422495-422956 [Dickeya fangzhongdai]
ATGACAAACTCAATTCTTGATAGCCTGAGCCTTCCGGCACCGGGGGAGATTGAGGCGGCTGTTCGTGGACAAAGGGAGCT
TGCTGCCTATCTCTCCACAAAGATGGAAACACAAAAAATCTCGATTCAGGATGCAGATAACAACACTCGTCAGGTCGAAT
TACCGACGTCGGCACTGACATTATTGATGTCGATTTTAGGCGAGCTGGCTGTGGGTAACGCGGTTCAGGTTGTTCCTGTT
CATGCTGAATTAACGACACAGGAGGCAGCCAACATTCTGAATGTTTCACGCCCTCACATGGTGAAGCTTCTGGAGGATGG
GAAACTACCTTTTCATAAAACCGGTCGCCACCGCCGTGTGCTTTTCGCTGACCTGATGGACTATAAACACCAGAGGGATA
ATGAAAGCAGTAGAGCAATGCAGGCGTTGGCAGATCATGGCCAAGAGCTTGGATTGTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References