Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2260273..2260811 Replicon chromosome
Accession NZ_CP025000
Organism Idiomarina sp. X4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CWC33_RS10920 Protein ID WP_058578973.1
Coordinates 2260273..2260572 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CWC33_RS10925 Protein ID WP_058578974.1
Coordinates 2260572..2260811 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CWC33_RS10880 2255840..2256295 + 456 WP_084342487.1 hypothetical protein -
CWC33_RS10885 2256432..2257070 + 639 WP_100691942.1 hypothetical protein -
CWC33_RS10890 2257060..2257767 + 708 WP_100691943.1 class I SAM-dependent methyltransferase -
CWC33_RS10895 2257851..2258222 + 372 WP_100691944.1 hypothetical protein -
CWC33_RS10900 2258332..2258892 + 561 WP_100691945.1 hypothetical protein -
CWC33_RS10905 2258987..2259256 + 270 WP_100691946.1 hypothetical protein -
CWC33_RS10910 2259279..2259785 + 507 WP_100691947.1 GNAT family N-acetyltransferase -
CWC33_RS10915 2259799..2260242 + 444 WP_100691948.1 CopD family protein -
CWC33_RS10920 2260273..2260572 - 300 WP_058578973.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CWC33_RS10925 2260572..2260811 - 240 WP_058578974.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CWC33_RS10930 2261016..2262263 + 1248 WP_100691949.1 acyl-CoA dehydrogenase family protein -
CWC33_RS10935 2262256..2263338 + 1083 WP_100691950.1 phosphotransferase family protein -
CWC33_RS10940 2263367..2264137 + 771 WP_100691951.1 SDR family oxidoreductase -
CWC33_RS10945 2264145..2264597 - 453 WP_100691952.1 hypothetical protein -
CWC33_RS10950 2264700..2264954 + 255 WP_100691953.1 hypothetical protein -
CWC33_RS10955 2264981..2265388 + 408 WP_088768004.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11533.22 Da        Isoelectric Point: 9.8622

>T89449 WP_058578973.1 NZ_CP025000:c2260572-2260273 [Idiomarina sp. X4]
VKPFQLTNKAKSDLKEIARFTSRRWGNEQRNVYLKQFDDSFWLLAEGPDIGKACDEIRDGYRKFPQGSHVIFYKQVGNQQ
IEIMRILHKSMDVAPIFGA

Download         Length: 300 bp

>T89449 NZ_CP025000:c2260572-2260273 [Idiomarina sp. X4]
GTGAAGCCCTTTCAACTCACTAATAAAGCAAAATCTGACTTAAAAGAGATAGCTCGGTTCACCTCACGCCGTTGGGGAAA
TGAGCAGCGGAATGTTTACCTCAAACAATTCGATGATTCTTTTTGGTTGTTAGCTGAGGGGCCGGATATTGGCAAAGCTT
GCGATGAAATCAGAGATGGGTACAGAAAATTCCCCCAAGGAAGTCACGTTATTTTTTATAAACAGGTTGGCAACCAGCAA
ATTGAGATCATGAGGATACTGCACAAAAGTATGGACGTTGCTCCTATTTTTGGAGCTTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8938.90 Da        Isoelectric Point: 4.1169

>AT89449 WP_058578974.1 NZ_CP025000:c2260811-2260572 [Idiomarina sp. X4]
MPKNTSITLGEHFDEFIANQLKTGRYGSASEVIRSALRLLETQETKVNTLRQLLVEGEESGMAEYDLDSFIDELDSEEK

Download         Length: 240 bp

>AT89449 NZ_CP025000:c2260811-2260572 [Idiomarina sp. X4]
ATGCCTAAAAATACTAGCATCACCCTTGGTGAGCATTTCGATGAGTTTATAGCTAATCAACTTAAAACTGGCCGATACGG
ATCCGCCAGTGAAGTCATTCGATCCGCTCTACGCTTACTCGAAACTCAGGAAACTAAAGTGAATACGCTGCGCCAACTTC
TGGTTGAAGGCGAAGAAAGTGGTATGGCTGAGTATGACCTCGACTCGTTTATCGATGAACTTGATAGCGAAGAGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References