Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1276299..1276975 Replicon chromosome
Accession NZ_CP025000
Organism Idiomarina sp. X4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CWC33_RS06100 Protein ID WP_100691214.1
Coordinates 1276299..1276748 (-) Length 150 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CWC33_RS06105 Protein ID WP_100691215.1
Coordinates 1276745..1276975 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CWC33_RS06085 1272110..1273378 + 1269 WP_100692289.1 deoxyguanosinetriphosphate triphosphohydrolase family protein -
CWC33_RS06090 1273375..1274082 + 708 WP_100691212.1 ZIP family metal transporter -
CWC33_RS06095 1274144..1276093 - 1950 WP_100691213.1 S8 family serine peptidase -
CWC33_RS06100 1276299..1276748 - 450 WP_100691214.1 type II toxin-antitoxin system VapC family toxin Toxin
CWC33_RS06105 1276745..1276975 - 231 WP_100691215.1 antitoxin Antitoxin
CWC33_RS06110 1277038..1278204 - 1167 WP_100691216.1 methyl-accepting chemotaxis protein -
CWC33_RS06115 1278403..1279059 + 657 WP_088767182.1 epoxyqueuosine reductase QueH -
CWC33_RS06120 1279124..1281250 - 2127 WP_100691217.1 TonB-dependent siderophore receptor -
CWC33_RS06125 1281321..1281791 - 471 WP_100691218.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-46)


Sequences

Toxin        


Download         Length: 150 a.a.        Molecular weight: 16950.25 Da        Isoelectric Point: 6.7450

>T89446 WP_100691214.1 NZ_CP025000:c1276748-1276299 [Idiomarina sp. X4]
MNLRYMLDTNICIYIMKNRPAYLAPIFDEHSRELCVSSVTVMELQYGVENSQQRVTNTDKLDSFLARLDILNYDADAAYH
TALIRHHLKKKGTPIGPYDQMIAGHARCHGLTVVTNNTGEFERVPGLISENWLQQPPQSSVNEPSPAYR

Download         Length: 450 bp

>T89446 NZ_CP025000:c1276748-1276299 [Idiomarina sp. X4]
ATGAATTTGCGATATATGCTGGATACCAATATCTGTATTTACATTATGAAGAACCGGCCTGCCTATTTAGCGCCTATTTT
TGATGAGCATTCTCGCGAACTCTGTGTAAGCTCAGTAACTGTCATGGAGCTTCAATACGGTGTCGAAAACTCTCAACAAC
GCGTTACTAATACCGACAAACTCGACAGCTTTTTAGCTCGCTTAGACATCCTCAACTACGATGCCGATGCGGCCTATCAT
ACGGCTCTTATCCGACATCATTTAAAAAAGAAAGGCACGCCCATTGGCCCTTATGATCAAATGATAGCAGGACACGCCAG
ATGCCATGGCCTAACCGTTGTAACTAACAATACAGGCGAGTTTGAACGCGTCCCTGGCTTAATTTCAGAGAATTGGTTAC
AGCAACCGCCGCAAAGTTCAGTGAATGAACCGAGCCCCGCCTACCGCTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8658.71 Da        Isoelectric Point: 4.3700

>AT89446 WP_100691215.1 NZ_CP025000:c1276975-1276745 [Idiomarina sp. X4]
MTKTTLFKSNKTQAVRLPKDVAFSEDVKEVEVLVVGESRIITPAKASWASWFSGEPASDDFMVEREQPEEQEREQL

Download         Length: 231 bp

>AT89446 NZ_CP025000:c1276975-1276745 [Idiomarina sp. X4]
ATGACCAAAACAACCCTTTTCAAAAGCAATAAAACGCAAGCGGTTCGGTTGCCAAAAGACGTCGCTTTTTCTGAAGACGT
AAAAGAAGTTGAGGTGTTAGTCGTTGGCGAAAGCCGAATTATTACCCCAGCGAAAGCCAGTTGGGCTTCTTGGTTTAGTG
GTGAACCTGCCAGTGACGACTTTATGGTTGAGCGTGAGCAGCCCGAAGAGCAGGAGCGCGAGCAGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References