Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 874823..875333 Replicon chromosome
Accession NZ_CP025000
Organism Idiomarina sp. X4

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag CWC33_RS04180 Protein ID WP_100690900.1
Coordinates 874823..875086 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CWC33_RS04185 Protein ID WP_100690901.1
Coordinates 875079..875333 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CWC33_RS04145 870272..870697 - 426 WP_100690893.1 helix-turn-helix transcriptional regulator -
CWC33_RS04150 870765..871949 - 1185 WP_100690894.1 GGDEF domain-containing protein -
CWC33_RS04155 872053..872493 - 441 WP_100690895.1 DUF2383 domain-containing protein -
CWC33_RS04160 872495..873394 - 900 WP_100690896.1 lipid kinase -
CWC33_RS04165 873505..873957 - 453 WP_100690897.1 acyltransferase -
CWC33_RS04170 873975..874265 - 291 WP_100690898.1 hypothetical protein -
CWC33_RS04175 874291..874698 - 408 WP_100690899.1 GFA family protein -
CWC33_RS04180 874823..875086 - 264 WP_100690900.1 Txe/YoeB family addiction module toxin Toxin
CWC33_RS04185 875079..875333 - 255 WP_100690901.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CWC33_RS04190 875457..875921 - 465 WP_100692269.1 GNAT family N-acetyltransferase -
CWC33_RS04195 875936..876544 - 609 WP_100690902.1 HAD-IB family hydrolase -
CWC33_RS04200 876638..877102 - 465 WP_157803477.1 hypothetical protein -
CWC33_RS04205 877293..877871 - 579 WP_100690904.1 hypothetical protein -
CWC33_RS04210 878082..878561 + 480 WP_100690905.1 transcription elongation factor GreB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10269.65 Da        Isoelectric Point: 9.8183

>T89444 WP_100690900.1 NZ_CP025000:c875086-874823 [Idiomarina sp. X4]
MSNRLLSWTDAAWKDYLFWQTQDKKTLKRINRLVADTKRSPFDGIGKPEPLKENLSGFWSRRIDDTNRLVYAADDSAITI
ISCRYHY

Download         Length: 264 bp

>T89444 NZ_CP025000:c875086-874823 [Idiomarina sp. X4]
ATGAGTAATCGGTTGCTGTCATGGACGGATGCAGCCTGGAAAGACTACTTATTTTGGCAAACTCAGGATAAAAAGACCCT
TAAACGTATTAACCGATTAGTTGCCGATACTAAGCGGTCGCCATTTGATGGTATTGGTAAGCCTGAACCGTTAAAAGAGA
ACCTTTCAGGATTCTGGTCTCGGCGAATTGATGACACTAATAGGCTGGTTTATGCGGCAGACGATAGTGCAATTACGATT
ATTTCGTGTCGGTATCATTACTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9496.71 Da        Isoelectric Point: 5.1007

>AT89444 WP_100690901.1 NZ_CP025000:c875333-875079 [Idiomarina sp. X4]
MRIVSFTEARNGLKAVLDSVINDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPANAEHLNKSIAQYKEGKAKQRE
LLDE

Download         Length: 255 bp

>AT89444 NZ_CP025000:c875333-875079 [Idiomarina sp. X4]
ATGAGAATCGTCTCTTTTACTGAAGCCAGAAACGGCTTAAAAGCTGTATTAGACAGTGTAATTAATGACGCTGACACTAC
GGTTATTACCCGTCGCGACTCGGAAGATGCCGTGGTGATGTCTTTGGATTACTACAATAGCTTAATGGAAACCGTCCACT
TGCTTCGTTCGCCAGCAAATGCTGAGCACTTGAATAAATCAATTGCTCAATACAAAGAAGGTAAAGCTAAGCAGCGAGAG
TTGTTAGATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References